Ondansetron Fresenius Kabi
Ondansetron Fresenius Kabi is a medicine used to prevent and treat nausea and vomiting caused by cancer treatment (chemotherapy or radiotherapy) or surgery.
How to Use
Dosage
For adults, the typical dose is 8-32 mg per day for cancer treatment, or 4 mg as a single dose for surgery. For children, your doctor will decide the right dose based on their weight or body surface area.
Method
This medicine is given as an infusion into a vein, usually by a doctor or nurse.
The maximum daily dose for adults is usually 32 mg, but it can be lower (e.g., 8 mg) if you have liver problems or are over 75 years old.
Possible Side Effects
- •Headache
- •Constipation
- •Feeling of warmth or flushing
- •Irritation or redness at the injection site
- •Chest pain, irregular heartbeat (arrhythmia that can be deadly), or slow heartbeat
- •Sudden chest pain or tightness in the chest (may be signs of reduced blood flow to the heart muscle)
- •Low blood pressure, making you feel weak or dizzy
- •Seizures
- •Unusual body movements or tremors
- •Hiccups
- •Changes in liver function tests
- •Sudden allergic reactions, including life-threatening reactions (anaphylaxis). Symptoms may include itchy rash, swelling of eyelids, face, lips, mouth, and tongue.
- •Feeling dizzy or faint
- •Blurred vision
- •Heart rhythm disorders, sometimes causing sudden loss of consciousness
- •Temporary blindness (usually resolves within 20 minutes)
- •Skin rash, e.g., red spots or bumps under the skin (hives) anywhere on the body, which can develop into large blisters.
Important Warnings
- Do not use this medicine if you are allergic to ondansetron, similar medicines (like granisetron or dolasetron), or any other ingredients in it.
- Do not use if you are taking apomorphine, a medicine for Parkinson's disease.
- Tell your doctor if you have had an allergic reaction to other anti-nausea medicines.
- Tell your doctor if you have a blocked bowel or severe constipation, as this medicine can slow down your bowel.
- Tell your doctor if you have liver problems, as your dose may need to be adjusted.
Show 5 more warnings
- Tell your doctor if you have recently had surgery to remove your tonsils.
- Tell your doctor if you have heart problems, such as an irregular heartbeat, or if your ECG shows a prolonged QT interval, as this medicine can affect your heart rhythm.
- Tell your doctor if you have problems with your blood salt levels, such as potassium, sodium, or magnesium.
- Do not use this medicine during the first three months of pregnancy as it may slightly increase the risk of a baby being born with a cleft lip or palate.
- Do not breastfeed while using this medicine, as ondansetron passes into breast milk.
Use in Elderly Patients
Suitable for older adults, with specific cautions. May prolong the QT interval especially with other preparations prolonging QT. Take interactions into account. (updated 20.5.2024)