Ondansetron B. Braun

Ondansetron B. Braun is a medicine used to prevent and treat nausea and vomiting caused by cancer treatment (chemotherapy or radiation) or surgery in adults and children.

Form
infuusioneste, liuos
Strength
0.16 mg/ml
Active Ingredient
Ondansetron hydrochloride dihydrate
Manufacturer
B. Braun Melsungen AG

How to Use

Dosage

For adults, typical doses are 8-32 mg daily for cancer treatment or a single 4 mg dose for post-surgery nausea. For children over 1 month, your doctor will decide the dose.

Method

This medicine is given as a short infusion into a vein, usually by a doctor or nurse.

Important

For adults, the maximum daily dose for cancer treatment is typically 32 mg, but for patients with liver problems, the maximum is 8 mg daily. Always follow your doctor's instructions.

Possible Side Effects

COMMON
  • Headache
  • Hot flushes or blushing
  • Constipation
  • Local reactions where the medicine is injected into your vein
RARE
  • Chest pain, irregular or slow heartbeat, or a squeezing sensation in the chest.
  • Severe allergic reactions, including sudden swelling of the hands, feet, face, lips, mouth, or throat, causing difficulty breathing or swallowing, accompanied by rash, itching, or hives.
  • Involuntary movements or tremors, such as uncontrolled eye movements, muscle spasms, or seizures.
  • Low blood pressure.
  • Hiccups.
  • Increased levels in liver function blood tests (usually without symptoms).
  • Hypersensitivity reactions at the injection site (e.g., rash, hives, itching).
  • Dizziness, especially when the medicine is given quickly into a vein.
  • Temporary changes in heart rhythm (visible on an ECG), especially after rapid intravenous administration.
  • Temporary vision disturbances, such as blurred vision, especially when the medicine is given quickly into a vein.
  • Depression.
  • Temporary blindness (reported in rare cases with certain cancer treatments, usually resolves within 20 minutes).

Important Warnings

  • Do not use if you are allergic to ondansetron or any other ingredients in this medicine.
  • Do not use if you are taking apomorphine, a medicine for Parkinson's disease.
  • Tell your doctor if you have a bowel blockage or severe constipation, as ondansetron can make these worse.
  • Inform your doctor if you have heart problems, irregular heartbeat, or problems with blood salt levels (potassium, sodium, magnesium).
  • Do not use this medicine during the first three months of pregnancy due to a slightly increased risk of cleft lip/palate in the baby.
Show 3 more warnings
  • Mothers should not breastfeed while receiving ondansetron treatment.
  • If you have severe liver problems, your doctor may need to adjust your dose.
  • Tell your doctor about all other medicines you are taking, especially certain epilepsy medicines, the antibiotic rifampicin, the painkiller tramadol, antidepressants, apomorphine, or medicines affecting heart rhythm.