Ondansetron B. Braun

Ondansetron B. Braun is a medicine that helps prevent and treat nausea and vomiting, especially after cancer treatments or surgery.

Form
infuusioneste, liuos
Strength
0.08 mg/ml
Active Ingredient
Ondansetron hydrochloride dihydrate
Manufacturer
B. Braun Melsungen AG

How to Use

Dosage

For adults, the usual dose for nausea caused by cancer treatments or radiation therapy is 8–32 mg per day; for nausea after surgery, a single dose of 4 mg is usually given.

Method

The medicine is given as a short drip (infusion) directly into a vein, usually by a doctor or nurse.

Important

For patients with liver problems, the maximum daily dose is 8 mg.

Possible Side Effects

COMMON
  • Headache.
  • Feeling hot or flushed.
  • Constipation.
  • Local reactions at the injection site.
RARE
  • Chest pain, irregular or slow heartbeat (which can sometimes be deadly).
  • Severe allergic reactions, including swelling of hands, feet, ankles, face, lips, mouth, or throat, causing difficulty breathing or swallowing, along with rash, itching, or hives.
  • Sudden chest pain or a tight feeling in the chest (heart ischemia).
  • Involuntary movements, like eye rolling, muscle twitching, or seizures.
  • Low blood pressure.
  • Hiccups.
  • Changes in liver function blood tests (usually without symptoms, especially in patients receiving cisplatin).
  • Allergic reactions at the injection site (e.g., rash, hives, itching).
  • Dizziness when the medicine is given quickly into a vein.
  • Temporary changes in heart rhythm seen on an ECG (especially after fast intravenous administration).
  • Temporary vision problems, like blurred vision, when the medicine is given quickly into a vein.
  • Depression.
  • Temporary blindness (reported in some patients receiving cisplatin, usually resolving within 20 minutes).

Important Warnings

  • Do not use if you are allergic to ondansetron or any other ingredients in this medicine.
  • Tell your doctor if you have allergies to other anti-nausea medicines, as you might also be allergic to this one.
  • Do not use if you are taking apomorphine (a medicine for Parkinson's disease).
  • Tell your doctor if you have a blocked bowel or severe constipation, as ondansetron can make these worse.
  • Tell your doctor if you have or have had heart problems, an irregular heartbeat, or issues with blood salt levels (like potassium, sodium, or magnesium).
Show 4 more warnings
  • Inform your doctor if you are having your tonsils removed.
  • Tell your doctor if you have liver problems.
  • Do not use this medicine during the first three months of pregnancy, as it may slightly increase the risk of your baby being born with a cleft lip and/or palate.
  • Do not breastfeed while taking this medicine, as ondansetron passes into breast milk.