Ondansetron Accordpharma

This medicine helps prevent and treat nausea and vomiting caused by cancer treatment (chemotherapy or radiation) and after surgery.

Form
injektio-/infuusioneste, liuos, esitäytetty ruisku
Strength
8 mg
Active Ingredient
Ondansetron hydrochloride dihydrate
Manufacturer
Accord Healthcare B.V.

How to Use

Dosage

Your doctor will decide your dose. For cancer treatment, adults usually get 8 mg as a slow injection before treatment, and another 8 mg 12 hours later. You might also take 8 mg by mouth twice a day for up to 5 days. For surgery, adults usually get 4 mg as a slow injection just before or after the operation.

Method

This medicine is given by a healthcare professional as an injection (into a vein or muscle) or an infusion (slow drip into a vein). You should never give it to yourself.

Important

A single dose should not be more than 16 mg. If you have liver problems, your total daily dose should not be more than 8 mg.

Possible Side Effects

COMMON
  • Headache
  • Flushing or feeling warm
  • Constipation
  • Irritation and redness at the injection site
RARE
  • Chest pain or tightness
  • Irregular or slow heartbeats
  • Seizures (fits)
  • Unusual body movements or tremors
  • Low blood pressure (making you feel dizzy or lightheaded)
  • Hiccups
  • Changes in liver function tests
  • Severe allergic reactions (with symptoms like itchy rash, swelling of eyelids, face, lips, mouth, or tongue)
  • Blurred vision or temporary vision loss
  • Severe skin rash with blisters and peeling (Toxic Epidermal Necrolysis)

Important Warnings

  • Do not use if you are allergic to ondansetron or similar anti-nausea medicines, or any other ingredient in this medicine.
  • Do not use if you are taking apomorphine (a medicine for Parkinson's disease).
  • Tell your doctor if you have a bowel blockage or severe constipation.
  • Tell your doctor if you have liver problems or are taking medicines that can harm your liver.
  • Tell your doctor if you have ever had heart problems, including irregular heartbeats.
Show 3 more warnings
  • Tell your doctor if you are having tonsil surgery, as this medicine can hide signs of bleeding.
  • Tell your doctor if you have problems with salt levels in your blood, like low potassium or magnesium.
  • Seek immediate medical help if you experience sudden chest pain or tightness.

Use in Elderly Patients

Category C

Suitable for older adults, with specific cautions. May prolong the QT interval especially with other preparations prolonging QT. Take interactions into account. (updated 20.5.2024)