Ondansetron Accord
Ondansetron Accord is a medicine that prevents and treats nausea and vomiting after certain medical treatments and surgeries.
Form
injektio/infuusioneste, liuos
Strength
2 mg/ml
Active Ingredient
Ondansetron hydrochloride dihydrate
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor or nurse will decide your dose, which is usually 4 mg or 8 mg for adults as a single dose, and for children, the dose is based on their weight or size.
Method
This medicine is usually given as an injection into a vein or a muscle.
Important
For adults, the maximum daily dose is usually 8 mg, especially if you have liver problems. For children, the maximum dose varies but is generally no more than 4 mg.
Possible Side Effects
COMMON
- •Headache
- •Feeling flushed or warm
- •Constipation
- •Changes in liver function tests
- •Irritation at the injection site (e.g., pain, burning, swelling, redness, itching)
RARE
- •Seizures (convulsions)
- •Unusual body movements or shaking (dyskinesia)
- •Muscle movement problems (dystonia)
- •Irregular or slow heartbeats
- •Chest pain
- •Fixed eye gaze
- •Low blood pressure, causing dizziness or fainting
- •Hiccups
- •Increased liver enzymes (seen in blood tests)
- •Severe allergic reactions
- •Dizziness or feeling confused during fast intravenous injection
- •Temporary vision problems (e.g., blurred or double vision)
- •Heart rhythm disturbances (sometimes leading to fainting)
- •Diarrhea and stomach pain
- •Very severe allergic reaction with fever, blistering, and peeling skin (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- •Poor vision or temporary blindness, usually lasting about 20 minutes
- •Fluid retention (swelling)
- •Rash and itching
- •Heart muscle ischemia (sudden chest pain or tightness)
Important Warnings
- Do not use this medicine if you are taking apomorphine (a medicine for Parkinson's disease).
- Tell your doctor if you are allergic to ondansetron, any other ingredients in this medicine, or similar medicines like granisetron or palonosetron.
- Tell your doctor if you have ever had heart problems, such as an irregular heartbeat.
- Tell your doctor if you have bowel problems.
- Do not use Ondansetron Accord during the first three months of pregnancy as it may slightly increase the risk of a baby being born with a cleft lip and/or palate.
Show 2 more warnings
- Breastfeeding is not recommended while taking this medicine, as it may pass into breast milk and affect your baby.
- Seek immediate medical help if you develop a severe allergic reaction, symptoms of which may include sudden wheezing, chest pain, swelling of the face, rash, or fainting. Stop using this medicine.
Use in Elderly Patients
Category C
Suitable for older adults, with specific cautions. May prolong the QT interval especially with other preparations prolonging QT. Take interactions into account. (updated 20.5.2024)