Olmesartan medoxomil/Amlodipine Krka
This medicine helps lower high blood pressure using two active ingredients, olmesartan medoxomil and amlodipine.
Form
tabletti, kalvopäällysteinen
Strength
20 mg / 5 mg
Active Ingredient
Olmesartan medoxomil
Manufacturer
KRKA d.d. Novo mesto
How to Use
Dosage
The recommended dose is one tablet once daily.
Method
Take the tablet with a small amount of liquid (e.g., a glass of water), with or without food. Do not chew the tablets. Do not take them with grapefruit juice. If possible, take your daily dose at the same time each day, for example, with breakfast.
Important
Do not take more than one tablet per day.
Possible Side Effects
COMMON
- •Dizziness
- •Headache
- •Swelling of ankles, feet, lower legs, hands or arms
- •Fatigue
RARE
- •Dizziness when standing up
- •Lack of energy
- •Tingling or numbness in hands or feet
- •Spinning sensation (vertigo)
- •Feeling your heart beat
- •Fast heart rate
- •Low blood pressure (may cause dizziness and fainting)
- •Breathing difficulties
- •Cough
- •Nausea
- •Vomiting
- •Indigestion
- •Diarrhea
- •Constipation
- •Dry mouth
- •Upper stomach pain
- •Rash
- •Muscle cramps
- •Arm and leg pain
- •Back pain
- •Increased need to urinate
- •Decreased sex drive
- •Inability to get or keep an erection
- •Weakness
- •Drug hypersensitivity
- •Fainting
- •Facial redness and warmth
- •Red itchy bumps (hives)
- •Facial swelling
- •Bronchitis
- •Sore throat
- •Runny or blocked nose
- •Stomach flu
- •Joint or bone pain
- •Blood in urine
- •Urinary tract infection
- •Chest pain
- •Flu-like symptoms
- •Pain
- •Changes in blood test results such as increased fat levels (hypertriglyceridemia), increased urea or uric acid in blood, and increased liver and muscle enzyme levels
- •Reduced white blood cells (increasing infection risk)
- •Reduced platelets (easier bruising, longer bleeding)
- •Sudden allergic reactions affecting the whole body, causing breathing difficulties and a rapid drop in blood pressure, potentially leading to fainting (anaphylactic reaction)
- •Chest pain during exertion (angina pectoris)
- •Itching
- •Skin reactions
- •Allergic rash
- •Muscle pain
- •Feeling unwell
- •Swelling of the face, mouth, and/or throat (vocal cords)
- •Sudden kidney dysfunction and kidney failure
- •Severe drowsiness
- •Intestinal angioedema: swelling of the intestine with symptoms like stomach pain, nausea, vomiting, and diarrhea
- •Swelling (fluid retention)
- •Ankle swelling
- •Drowsiness
- •Vision problems (including double vision and blurred vision)
- •Muscle cramps
- •Sleep problems
- •Insomnia
- •Mood changes (like anxiety, depression, irritability)
- •Chills
- •Changes in taste
- •Ringing in ears (tinnitus)
- •Worsening of chest pain (angina pectoris)
- •Irregular heartbeat
- •Hair loss
- •Purple spots or patches on skin due to small bleeds (purpura)
- •Skin discoloration
- •Excessive sweating
- •Difficulty urinating
- •Needing to urinate at night
- •Breast enlargement in men
- •Weight gain or loss
- •Confusion
- •Increased blood sugar
- •Increased muscle tone or resistance to movement (hypertonia)
- •Heart attack
- •Blood vessel inflammation
- •Pancreas or liver inflammation
- •Stomach lining inflammation
- •Gum thickening
- •Increased liver enzymes
- •Yellow skin or eyes
- •Increased skin sensitivity to light
- •Severe skin reactions, including severe rash, hives, widespread skin redness, severe itching, blistering, peeling, and swelling, mucous membrane inflammation (Stevens-Johnson syndrome, toxic epidermal necrolysis), which can sometimes be life-threatening
- •Tremor
- •Body stiffness
- •Mask-like face
- •Slow movements
- •Shuffling and unbalanced gait
Important Warnings
- Do not use if you are allergic to olmesartan medoxomil, amlodipine, dihydropyridine calcium channel blockers, or any other ingredients in this medicine.
- Do not use if you are more than 3 months pregnant. It is also best to avoid this medicine during early pregnancy.
- Do not use if you have diabetes or kidney problems and are taking aliskiren for high blood pressure.
- Do not use if you have severe liver disease, reduced bile flow, blocked bile ducts (e.g., due to gallstones), or jaundice (yellow skin/eyes).
- Do not use if you have very low blood pressure.
Show 6 more warnings
- Do not use if your tissues are not getting enough blood, leading to symptoms like low blood pressure, slow pulse, or fast heartbeat (shock, including cardiogenic shock).
- Do not use if blood flow from your heart is blocked (e.g., due to a narrowing of the aorta).
- Do not use if you have low cardiac output (causing shortness of breath or swelling in limbs) after a heart attack.
- Stop taking this medicine and contact a doctor immediately if you experience allergic reactions like swelling of the face, mouth, and/or throat, itching, and rash.
- Stop taking this medicine, contact a doctor immediately, and lie down if you experience severe dizziness or fainting, which can be caused by very low blood pressure or an allergic reaction.
- Contact a doctor immediately if you notice yellowing of the whites of your eyes, dark urine, or itchy skin, even if you have been taking this medicine for a long time.