Olanzapine Accord
Olanzapine Accord is an antipsychotic medicine used to treat schizophrenia and bipolar disorder, helping to prevent symptoms from returning.
Form
tabletti, kalvopäällysteinen
Strength
10 mg
Active Ingredient
Olanzapine
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor will prescribe the right dose for you, usually 5 mg to 20 mg per day.
Method
Take one tablet once a day, swallowed whole with water, with or without food.
Important
The maximum daily dose is 20 mg.
Possible Side Effects
COMMON
- •Weight gain
- •Drowsiness or sleepiness
- •Increased prolactin levels in blood
- •Dizziness or faintness (especially when standing up, with slow heart rate)
- •Changes in blood cell counts and blood fat levels
- •Temporary increase in liver enzyme levels at the start of treatment
- •Increased blood sugar and sugar in urine
- •Increased uric acid and creatinine phosphokinase in blood
- •Increased appetite
- •Restlessness
- •Tremor (shaking)
- •Unusual movements (dyskinesia)
- •Constipation
- •Dry mouth
- •Rash
- •Weakness
- •Extreme tiredness
- •Fluid retention and swelling in hands, ankles, or feet
- •Fever
- •Joint pain
- •Sexual problems, such as decreased sex drive in men and women or erection problems in men
RARE
- •Allergy (e.g., swelling of mouth/throat, itching, rash)
- •Onset or worsening of diabetes, sometimes with ketoacidosis or coma
- •Seizures (usually in patients with a history of epilepsy)
- •Muscle stiffness and spasms (including eye movements)
- •Restless legs syndrome
- •Speech problems
- •Stuttering
- •Slow heart rate
- •Sensitivity to sunlight
- •Nosebleed
- •Abdominal bloating
- •Drooling
- •Memory loss or forgetfulness
- •Urinary incontinence
- •Difficulty urinating
- •Hair loss
- •Absent or reduced menstrual periods
- •Breast changes in men and women (e.g., abnormal milk production or breast enlargement)
- •Decrease in body temperature
- •Heart rhythm disorders
- •Sudden unexplained death
- •Pancreatitis (severe stomach pain, fever, and vomiting)
- •Liver disease (yellowing of skin and whites of eyes)
- •Muscle disorder (unexplained aches and pains)
- •Prolonged and painful erection
Important Warnings
- Do not use if you are allergic to olanzapine or any other ingredients in this medicine. Allergic reactions can include rash, itching, swelling of the face or lips, or trouble breathing. Contact your doctor immediately.
- Do not use if you have or have had eye problems, such as certain types of glaucoma (high pressure in the eye).
- Not recommended for elderly patients with dementia due to risk of serious side effects.
- If you develop unusual movements, especially of the face or tongue, tell your doctor right away.
- Contact your doctor immediately if you develop a combination of fever, fast breathing, sweating, muscle stiffness, and drowsiness.
Show 4 more warnings
- Tell your doctor if you or anyone in your family has had blood clots, as this medicine can increase the risk.
- Do not drink alcohol while taking Olanzapine Accord, as it can increase drowsiness.
- Do not drive or operate machinery if this medicine makes you drowsy.
- Do not use if you are breastfeeding, as the medicine can pass into breast milk.
Use in Elderly Patients
Category D
Avoid use in older adults. Anticholinergic. Sedative. For treatment of psychosis only. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)