Olanzapin Sandoz

Olanzapin Sandoz is a medicine used to treat schizophrenia and manic episodes in bipolar disorder, helping to manage symptoms like hallucinations and mood swings.

Form
tabletti, kalvopäällysteinen
Strength
15 mg
Active Ingredient
Olanzapine
Manufacturer
Sandoz A/S

How to Use

Dosage

Your doctor will decide your dose, usually 5-20 mg per day.

Method

Take one tablet once a day with water, with or without food. Try to take it at the same time each day.

Important

The maximum daily dose is usually 20 mg.

Possible Side Effects

COMMON
  • Weight gain
  • Drowsiness or sleepiness
  • Increased prolactin levels in blood
  • Feeling dizzy or faint, especially when standing up (with a slow heartbeat at first)
  • Changes in some blood cell counts and blood fat levels
  • Temporary increase in liver enzymes
  • Increased blood sugar and sugar in urine
  • Increased uric acid and creatine phosphokinase in blood
  • Increased appetite
  • Dizziness
  • Restlessness
  • Tremor
  • Unusual movements (dyskinesia)
  • Constipation
  • Dry mouth
  • Rash
  • Weakness
  • Extreme tiredness
  • Fluid retention leading to swelling in hands, ankles, or feet
  • Fever
  • Joint pain
  • Sexual problems, like reduced sex drive or erectile dysfunction
RARE
  • Allergic reactions (like swelling of mouth/throat, itching, rash)
  • New or worsening diabetes, sometimes with severe complications like ketoacidosis or coma
  • Seizures (fits), especially if you have a history of them
  • Muscle stiffness and spasms (including eye movements)
  • Restless legs syndrome
  • Speech problems
  • Stuttering
  • Slow heartbeat
  • Sensitivity to sunlight
  • Nosebleed
  • Bloating
  • Drooling
  • Memory loss or forgetfulness
  • Urinary incontinence or trouble urinating
  • Hair loss
  • Missed or shorter menstrual periods
  • Breast changes in men and women (e.g., unusual milk production or enlargement)
  • Reduced body temperature
  • Abnormal heart rhythm
  • Sudden unexplained death
  • Inflammation of the pancreas (severe stomach pain, fever, vomiting)
  • Liver disease (yellowing of skin or eyes)
  • Muscle disease (unexplained aches and pains)
  • Prolonged or painful erection
  • Blood clots, especially in the legs (symptoms include swelling, pain, redness) which can travel to the lungs and cause chest pain and trouble breathing

Important Warnings

  • Do not take if you are allergic to olanzapine or have certain eye problems like glaucoma.
  • This medicine is not recommended for elderly patients with dementia due to serious side effects.
  • If you get unusual movements, especially of the face or tongue, tell your doctor.
  • If you experience fever, fast breathing, sweating, muscle stiffness, and drowsiness, contact your doctor right away.
  • You may gain weight or have high blood sugar or fat levels. Your doctor will check these regularly.
Show 5 more warnings
  • Tell your doctor if you or your family has a history of blood clots, as this medicine can cause them.
  • Do not drink alcohol while taking this medicine, as it can make you very drowsy.
  • This medicine can make you drowsy. Do not drive or use machines if you feel drowsy.
  • If you are pregnant, planning to be, or breastfeeding, talk to your doctor before taking this medicine.
  • Do not stop taking this medicine suddenly, even if you feel better. Your doctor will tell you how to stop safely.

Use in Elderly Patients

Category D

Avoid use in older adults. Anticholinergic. Sedative. For treatment of psychosis only. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)