Olanzapin Ratiopharm

Olanzapin ratiopharm is a medicine used to treat mental health conditions like schizophrenia and moderate to severe manic episodes in bipolar disorder.

Form
tabletti, suussa hajoava
Strength
20 mg
Active Ingredient
Olanzapine
Manufacturer
Teva B.V.

How to Use

Dosage

Your doctor will decide your dose, usually between 5 mg and 20 mg per day.

Method

Take your tablet once a day, at the same time, with or without food. Place the tablet in your mouth; it dissolves quickly. You can also dissolve it in a glass of water, juice, milk, or coffee.

Important

The daily dose typically ranges from 5 mg to 20 mg as prescribed by your doctor. Do not exceed this dose.

Possible Side Effects

COMMON
  • Unusual movements, especially of the face or tongue.
  • Weight gain, drowsiness, and increased levels of prolactin in the blood.
  • Dizziness or fainting, especially when standing up.
  • Changes in blood cell counts and blood fat levels, and temporary increases in liver enzymes at the start of treatment.
  • Increased blood and urine sugar levels; increased uric acid and creatine phosphokinase levels in the blood.
  • Increased appetite, dizziness, restlessness, tremor, unusual movements (dyskinesia), constipation, dry mouth, rash, weakness, severe tiredness, fluid retention causing swelling in hands, ankles or feet, fever, joint pain, and sexual problems including decreased sex drive and erectile dysfunction in men.
RARE
  • Blood clots in veins, especially in the legs (symptoms include swelling, pain, redness in the leg). These can travel to the lungs, causing chest pain and breathing difficulties.
  • A combination of fever, fast breathing, sweating, muscle stiffness, and drowsiness.
  • Allergic reactions (e.g., swelling of mouth and throat, itching, rash), onset or worsening of diabetes (sometimes with ketoacidosis or coma), seizures (especially in patients with a history of seizures), muscle stiffness and spasms (including eye movements), restless legs syndrome, speech difficulties, stuttering, slow heart rate, sensitivity to sunlight, nosebleeds, abdominal bloating, drooling, memory loss, urinary incontinence, difficulty urinating, hair loss, missed or irregular periods, and breast changes in men and women (e.g., unusual milk production or breast enlargement).
  • Decreased body temperature, abnormal heart rhythm, unexplained sudden death, pancreatitis (symptoms include severe stomach pain, fever, and vomiting), liver disease (yellowing of skin and whites of eyes), unexplained muscle pain or soreness, and prolonged or painful erection.
  • Severe allergic reactions like DRESS syndrome, which starts with flu-like symptoms and rash on the face, followed by widespread rash, high fever, swollen lymph nodes, increased liver enzyme levels, and an increase in a certain type of white blood cell (eosinophilia).

Important Warnings

  • Do not take this medicine if you are allergic to olanzapine or any other ingredients, or if you have a certain type of glaucoma.
  • This medicine is not recommended for elderly patients with dementia due to serious side effects.
  • This medicine can cause unusual movements, especially of the face or tongue. Tell your doctor if this happens.
  • Rarely, this medicine can cause fever, fast breathing, sweating, stiff muscles, or severe drowsiness. Contact your doctor immediately if these symptoms occur.
  • Weight gain has been reported with this medicine. Your doctor will monitor your weight regularly.
Show 6 more warnings
  • High blood sugar and fat levels have occurred. Your doctor will check your blood sugar and fat levels with blood tests before and during treatment.
  • Tell your doctor if you or your family has a history of blood clots, as this medicine can increase the risk.
  • Inform your doctor immediately if you have had a stroke, Parkinson's disease, prostate problems, bowel obstruction, liver or kidney disease, blood or heart disease, diabetes, seizures, or if you have severe diarrhea, vomiting, or use diuretics.
  • Do not drink alcohol while on this medicine, as it can increase drowsiness.
  • Do not breastfeed while taking this medicine, as it can pass into breast milk.
  • This medicine may make you drowsy. Do not drive or operate machinery if you feel drowsy.

Use in Elderly Patients

Category D

Avoid use in older adults. Anticholinergic. Sedative. For treatment of psychosis only. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)