Olanzapin Ratiopharm
This medicine contains olanzapine and is used to treat mental health conditions like schizophrenia and manic episodes in bipolar disorder, helping to prevent their return.
Form
tabletti, suussa hajoava
Strength
5 mg
Active Ingredient
Olanzapine
Manufacturer
Teva B.V.
How to Use
Dosage
Your doctor will tell you the right dose, usually between 5 mg and 20 mg per day.
Method
Take one tablet once a day at the same time, with or without food. Place the fragile tablet in your mouth; it dissolves quickly and can then be swallowed. You can also dissolve it in water, juice, milk, or coffee and drink it immediately.
Important
Do not exceed the dose prescribed by your doctor, usually 20 mg per day.
Possible Side Effects
COMMON
- •Weight gain
- •Drowsiness or sleepiness
- •Increased levels of a hormone called prolactin in the blood
- •Dizziness or faintness, sometimes with a slow heartbeat, especially when standing up from lying or sitting
- •Changes in blood cell and blood fat levels
- •Temporary increase in liver enzymes at the start of treatment
- •Increased blood sugar and sugar in urine
- •Increased uric acid and creatine phosphokinase levels in blood
- •Increased appetite
- •Restlessness
- •Tremor (shaking)
- •Unusual movements (dyskinesia)
- •Constipation
- •Dry mouth
- •Rash
- •Weakness
- •Severe tiredness
- •Fluid retention, causing swelling in hands, ankles, or feet
- •Fever
- •Joint pain
- •Problems with sexual function, like decreased sex drive or erectile dysfunction in men
RARE
- •Allergic reactions, including swelling of the mouth or throat, itching, or rash
- •New onset or worsening diabetes, sometimes with serious complications like ketoacidosis or coma
- •Seizures (fits), especially if you have had them before
- •Muscle stiffness or spasms, including eye movements
- •Restless legs syndrome
- •Problems with speech
- •Stuttering
- •Slow heartbeat
- •Increased sensitivity to sunlight
- •Nosebleed
- •Swollen abdomen
- •Drooling
- •Memory loss or forgetfulness
- •Leaking urine (urinary incontinence)
- •Difficulty urinating
- •Hair loss
- •Missed or reduced menstrual periods
- •Breast changes in men and women, such as abnormal milk production or breast enlargement
- •Decrease in body temperature
- •Abnormal heartbeat
- •Sudden, unexplained death
- •Inflammation of the pancreas, causing severe stomach pain, fever, and vomiting
- •Liver disease causing yellowing of the skin or eyes
- •Muscle disease causing unexplained pain
- •Prolonged or painful erection
- •Very rare but severe allergic reaction (DRESS), starting with flu-like symptoms and a rash on the face, then widespread rash, high fever, swollen lymph nodes, high liver enzymes, and increased white blood cells (eosinophils).
- •Worsening of Parkinson's disease symptoms in patients with Parkinson's.
Important Warnings
- Do not take if you are allergic to olanzapine or any other ingredients.
- Do not take if you have a history of certain eye conditions like glaucoma (high pressure in the eye).
- This medicine is not recommended for elderly patients with dementia due to serious side effects like stroke or pneumonia.
- This medicine can cause unusual movements, especially of the face or tongue. Tell your doctor if this happens.
- In rare cases, this medicine can cause a combination of fever, rapid breathing, sweating, stiff muscles, and extreme tiredness. Contact a doctor immediately if you experience these.
Show 8 more warnings
- Weight gain has been observed. Your weight should be monitored regularly by you and your doctor.
- High blood sugar and fat levels have been observed. Your doctor will check these levels regularly.
- Tell your doctor if you or your family have a history of blood clots, as this medicine can increase the risk of clots.
- Do not drink alcohol while taking this medicine, as it can cause severe drowsiness.
- If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor. This medicine should not be taken during breastfeeding.
- This medicine can make you sleepy, affecting your ability to drive or use machines. Be careful until you know how it affects you.
- Always tell your doctor about other health conditions you have, such as stroke, Parkinson's disease, diabetes, or heart problems.
- If you are over 65, your doctor should check your blood pressure regularly.
Use in Elderly Patients
Category D
Avoid use in older adults. Anticholinergic. Sedative. For treatment of psychosis only. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)