Olanzapin Orion
Olanzapin Orion is a medicine used to treat mental health conditions like schizophrenia (which can cause hallucinations and unusual thoughts) and severe mood swings (mania) in bipolar disorder.
How to Use
Dosage
Your doctor will tell you how much to take, typically between 5-20 mg once daily.
Method
Take one tablet by mouth once daily. You can take it with or without food, preferably at the same time each day. The tablet dissolves easily in your mouth or can be mixed into a drink like water or juice and consumed immediately.
Do not take more than 20 mg in a single day.
Possible Side Effects
- •Weight gain
- •Drowsiness
- •Increased prolactin levels in blood
- •Changes in blood cell counts, fat levels, and temporary increase in liver enzymes at the start of treatment
- •Increased blood and urine sugar levels
- •Increased uric acid and creatine phosphokinase levels in blood
- •Increased appetite
- •Dizziness
- •Restlessness
- •Tremor (shaking)
- •Abnormal movements (dyskinesia)
- •Constipation
- •Dry mouth
- •Rash
- •Weakness
- •Severe tiredness
- •Fluid retention (swelling of hands, ankles, or feet)
- •Fever
- •Joint pain
- •Sexual problems (decreased sex drive in men and women, erectile dysfunction in men)
- •Hypersensitivity (e.g., swelling of mouth and throat, itching, rash)
- •New or worsening diabetes, sometimes with ketoacidosis or coma
- •Seizures (epilepsy), generally in patients with a history of seizures
- •Muscle stiffness and spasms (including eye movements)
- •Restless legs syndrome
- •Speech difficulties
- •Stuttering
- •Slow heart rate
- •Sensitivity to sunlight
- •Nosebleed
- •Abdominal distension
- •Drooling
- •Memory impairment or forgetfulness
- •Urinary incontinence or difficulty urinating
- •Hair loss
- •Missed or irregular periods
- •Breast changes (e.g., abnormal milk production or enlargement in men and women)
- •Decrease in body temperature
- •Abnormal heart rhythm
- •Unexplained sudden death
- •Pancreatitis (severe stomach pain, fever, and vomiting)
- •Liver disease (yellowing of skin and eyes)
- •Muscle disease (unexplained aches and pains)
- •Prolonged or painful erection
Important Warnings
- Do not take if you are allergic to olanzapine or any other ingredient.
- Do not take if you have a history of certain eye problems, like glaucoma.
- This medicine is not recommended for elderly patients with dementia due to serious side effects.
- This type of medicine can cause unusual movements of the face or tongue; tell your doctor if this happens.
- Rarely, this medicine can cause a combination of fever, fast breathing, sweating, stiff muscles, and drowsiness; contact your doctor immediately if these symptoms occur.
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- Weight gain has been reported; your weight should be monitored regularly.
- High blood sugar and fat levels have been reported; your doctor will check these with blood tests.
- Tell your doctor if you or a family member have a history of blood clots, as this medicine can increase the risk.
- Inform your doctor as soon as possible if you have or have had a stroke, Parkinson's disease, prostate problems, bowel obstruction (paralytic ileus), liver or kidney disease, blood disorders, heart disease, diabetes, or seizures.
- Do not drink alcohol while taking this medicine, as it can increase drowsiness.
- This medicine can cause drowsiness. Do not drive or operate machinery if you feel drowsy.
- Do not stop taking this medicine suddenly, even if you feel better, unless your doctor tells you to. Stopping abruptly can cause withdrawal symptoms like sweating, trouble sleeping, shaking, anxiety, nausea, or vomiting.
- If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Do not breastfeed while taking this medicine as it can pass into breast milk.
Use in Elderly Patients
Avoid use in older adults. Anticholinergic. Sedative. For treatment of psychosis only. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)