Nomigrin
Nomigrin contains sumatriptan and naproxen sodium, used to treat migraine headaches in adults by narrowing blood vessels and reducing pain.
Form
tabletti, kalvopäällysteinen
Strength
85 mg / 500 mg
Active Ingredient
Sumatriptan succinate
Manufacturer
Orion Corporation
How to Use
Dosage
Take one tablet as soon as migraine symptoms start. If the headache returns or only partly goes away, you can take a second tablet after two hours.
Method
Swallow the tablets whole with water. Do not chew or crush them. You can take them with or without food.
Important
Do not take more than two doses (tablets) in a 24-hour period. If the first dose doesn't help, do not take another. If you have mild liver or kidney problems, take only one tablet per day.
Possible Side Effects
COMMON
- •Pain in the upper stomach.
- •Nausea, heartburn, constipation, indigestion, diarrhea, inflammation of the mouth lining.
- •Dizziness, tingling, drowsiness, altered sensations, headache, strange or unreal feeling.
- •Vision problems, ringing in the ears, hearing problems.
- •Worsening heart failure (swelling, shortness of breath), temporary blood pressure increase, flushing.
- •Breathing difficulties.
- •Skin problems (itching, rash, red spots), bruising, increased sweating.
- •Muscle pain.
- •Pain, feeling hot or cold, pressure or tightness, weakness, tiredness.
RARE
- •Increased potassium levels, fluid retention (swelling).
- •Mood changes, depression, poor concentration, memory problems, sleep difficulties or changes in dream patterns.
- •Seizures or epileptic fits.
- •Irregular heartbeat (palpitations).
- •Increased liver enzyme and bilirubin levels (jaundice).
- •Menstrual disorders.
- •Thirst.
- •Stomach bleeding, seen as vomiting blood or particles resembling coffee grounds.
- •Rectal bleeding, appearing as black, sticky stools or bloody diarrhea.
- •Ulcers or holes in the stomach or intestines. Symptoms include stomach upset, abdominal pain, fever, nausea, or vomiting.
- •Worsening of ulcerative colitis or Crohn's disease, with pain, diarrhea, vomiting, and weight loss.
- •Rapidly developing severe allergic reaction causing breathing difficulties or dizziness (anaphylactic reaction).
- •Swelling of face, tongue, or throat, difficulty swallowing, hives, and breathing difficulties (angioedema).
- •Tiredness, loss of appetite, nausea or vomiting, pain or swelling in the upper right abdomen, dark urine, pale stools, and yellowing of the skin or whites of the eyes (toxic hepatitis).
- •Hearing loss.
- •Fluid accumulation in the lungs.
- •Worsening of asthma.
- •Hair loss.
- •Increased skin sensitivity to sunlight, blistering, and skin changes (pseudoporphyria).
- •Muscle weakness, muscle pain.
- •Breast pain.
- •Pancreas problems, with severe abdominal pain radiating to the back.
- •Initial flu-like symptoms (feeling unwell, fever, headache, cough, and joint pain), followed by rapidly spreading red or purplish rash with painful blisters and peeling skin, and possibly blisters in the mouth, throat, eyes, or genital area (Stevens-Johnson syndrome/toxic epidermal necrolysis).
- •Fever, nausea or vomiting, stiff neck, headache, sensitivity to bright light, and confusion (mostly in people with autoimmune diseases).
- •Chest pain that can spread to the neck, shoulders, and left arm.
- •Muscle weakness and numbness (only on one side of the body), sudden changes in smell, taste, hearing, or vision, confusion.
- •Widespread rash, fever, raised liver enzymes, abnormal blood counts, swollen lymph nodes, and effects on other organs.
- •A specific allergic skin reaction that usually appears in the same spots as round or oval, red or swollen patches, blisters, or itchy marks.
- •Anxiety.
- •Involuntary movements (dystonia), shaking, eye twitching (nystagmus).
- •Heart rhythm problems, faster or slower heart rate, chest pain (angina pectoris).
- •Low blood pressure, Raynaud's phenomenon (fingers and toes turning white and numb).
- •Difficulty swallowing.
- •Excessive sweating.
- •Stiff neck, joint pain.
- •Pain or worsening pain at an injury or inflammation site, fever.
- •Skin disease with red itchy patches usually on palms, soles, and face (erythema multiforme), worsening of skin diseases (e.g., lichen planus, erythema nodosum, SLE).
- •Blood or protein in urine, impaired kidney function, kidney inflammation, or other kidney disorders.
- •Blood problems, such as anemia, changes in white blood cells, low platelet count, changes in blood cell counts.
- •Worsening of Parkinson's disease.
- •Blood vessel inflammation.
- •Lung inflammation.
- •Swollen salivary glands.
- •Slight abnormalities in liver function tests.
Important Warnings
- You are allergic to sumatriptan, naproxen, or any other ingredients in this medicine.
- You are allergic to aspirin or other anti-inflammatory pain relievers (like ibuprofen), or have had an allergic reaction (e.g., rash, itching, asthma symptoms) to them before.
- You have or have had heart problems, such as severe heart failure, narrowed arteries (ischemic heart disease), chest pain during exercise, or a heart attack.
- You have high blood pressure. (Your doctor might decide you can use Nomigrin if your blood pressure is only slightly high and treated).
- You have had a stroke or a mini-stroke (TIA), as your risk might be higher.
Show 10 more warnings
- You have circulation problems in your legs causing cramp-like pain when walking.
- You have or have had stomach or duodenal ulcers, or bleeding from your stomach or intestines while using anti-inflammatory pain relievers.
- Your kidney or liver function is severely impaired.
- You are using other migraine medicines like ergotamine, methysergide maleate, or other triptans (such as naratriptan or zolmitriptan). There must be a 24-hour gap between taking these medicines and Nomigrin.
- You have used MAO inhibitors (for depression or Parkinson's disease) within the last two weeks or are using them now.
- You are in the last three months of pregnancy. Nomigrin can harm your unborn baby or cause problems during delivery.
- Do not breastfeed your baby for at least 12 hours after taking Nomigrin.
- Only use Nomigrin if you are sure your headache is a migraine. If your headache is different from your usual headaches, talk to your doctor first.
- If you experience short-lasting chest pain or a tight feeling in your chest after taking Nomigrin and the symptoms do not ease, contact your doctor.
- Stop taking Nomigrin immediately and contact your doctor if you experience severe skin reactions, such as rash, fever, or blisters.