Nitrosid Retard
Nitrosid retard capsules are used to treat coronary artery disease and heart failure.
Form
depotkapseli, kova
Strength
20 mg
Active Ingredient
Isosorbide dinitrate
Manufacturer
Orion Corporation
How to Use
Dosage
For coronary artery disease: 1-4 capsules, 1-2 times a day. For heart failure: 2-4 capsules, 1-2 times a day. Your doctor might prescribe a different dose.
Method
Swallow the capsule whole, do not chew. If needed, you can open the capsule and swallow its contents with food or drink. If taking twice a day, take the first dose in the morning and the second dose 6 hours later.
Important
Up to 8 capsules per day, unless your doctor has given different instructions.
Possible Side Effects
COMMON
- •headache
COMMON
- •confusion
- •dizziness
- •drowsiness
- •fast heartbeat
- •low blood pressure
- •feeling weak
RARE
- •worsening chest pain (angina)
- •facial flushing
- •circulation problems
- •nausea
- •vomiting
- •allergic skin reactions
RARE
- •restlessness
- •fainting
- •slow heartbeat
- •temporary heart conduction disorder
- •methemoglobinemia (a blood disorder)
RARE
- •heartburn
- •severe skin reactions
Important Warnings
- Do not take if you are allergic to isosorbide dinitrate, other nitrates, or any other ingredients in this medicine.
- Do not take if you have very low blood pressure.
- Do not take if you have certain severe heart conditions like severe heart valve problems, cardiac tamponade, or cardiogenic shock.
- Do not take if you have acute circulation problems or severe untreated anemia.
- Do not take if you have high pressure inside your head.
Show 8 more warnings
- Do not take if you are using medicines for erectile dysfunction (like sildenafil, vardenafil, or tadalafil) as this can be life-threatening.
- Do not take if you are using riociguat (a medicine for pulmonary hypertension).
- Talk to your doctor before taking if you have recently had a heart attack or have lung problems causing low oxygen.
- This medicine can make the effects of other blood pressure lowering medicines stronger.
- Avoid alcohol as it can further lower your blood pressure.
- Do not give this medicine to children as its safety and effectiveness have not been proven for them.
- If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
- This medicine may make you feel dizzy or sleepy, affecting your ability to drive or operate machinery.
Use in Elderly Patients
Category A
Suitable for older adults. Consider reduced blood pressure and the risk of fainting due to orthostatic hypotonia. Need for long-acting product should be assessed regularly. (updated 19.5.2025)