Nitisinone Dipharma
Nitisinone Dipharma helps treat rare diseases like hereditary tyrosinemia type 1 and alkaptonuria (AKU) by stopping the body from breaking down tyrosine, which prevents harmful substances from building up.
How to Use
Dosage
For hereditary tyrosinemia type 1, the usual dose is 1 mg per kg of body weight daily. For AKU, the recommended dose is 10 mg once daily. Your doctor will adjust your dose.
Method
Take this medicine exactly as your doctor tells you. You can take it once a day. If you weigh less than 20 kg, your daily dose might be split into two. If you have trouble swallowing capsules, you can open them and mix the contents with a small amount of water, apple juice, applesauce, or liquid formula right before taking. Always take with food if you start that way.
The maximum daily dose for hereditary tyrosinemia type 1 is usually 1 mg per kg of body weight. For AKU, it is 10 mg per day. Your doctor will determine the correct dose for you.
Possible Side Effects
- •Eye inflammation
- •Cloudy cornea
- •Light sensitivity
- •Eye pain
- •Low platelet count
- •Low white blood cell count
- •Lack of certain white blood cells
- •Bronchitis
- •Pneumonia
- •Itching
- •Rash
- •Eyelid inflammation
- •High white blood cell count
- •Skin inflammation
Important Warnings
- Do not take if you are allergic to nitisinone or any other ingredient in this medicine.
- Your eyes will be checked by an eye doctor before and regularly during treatment. If you experience eye problems, contact your doctor immediately. This could mean your diet is not working well.
- You will have regular blood tests to check if the treatment is working and to monitor for side effects.
- If you are taking this for hereditary tyrosinemia type 1, your liver will be checked regularly because the disease affects the liver.
- Tell your doctor about all other medicines you take, as Nitisinone Dipharma can affect some epilepsy and blood-thinning medicines.
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- Do not breastfeed while taking this medicine. Talk to your doctor if you plan to get pregnant or become pregnant.
- If this medicine affects your eyesight, do not drive or use machines until your vision returns to normal.