Nexodal
Nexodal is a medicine used to reverse the effects of an opioid overdose, such as from too much morphine.
Form
injektio-/infuusioneste, liuos
Strength
0.4 mg/ml
Active Ingredient
Naloxone hydrochloride
Manufacturer
Orpha-Devel Handels und Vertriebs GmbH
How to Use
Dosage
For adults, the doctor will usually give 0.4 to 2 mg of naloxone into a vein. More doses might be given every 2-3 minutes if needed.
Method
A doctor or nurse will give Nexodal as a shot into a vein or muscle, or as a drip into a vein. Shots into a muscle are only used if a vein shot is not possible.
Important
Your doctor will decide how long you need to take this medicine and what your maximum daily dose should be.
Possible Side Effects
COMMON
- •Feeling sick or unwell
- •Dizziness, headache, fast heartbeat, low or high blood pressure, throwing up, pain after surgery
RARE
- •Shivers, sweating, irregular or slow heartbeat, diarrhea, dry mouth, fast and deep breathing, irritation where the shot was given in a vein
- •Seizures, feeling nervous
- •Very fast or uneven heartbeat, heart stopping, fluid in the lungs, allergic reactions (like hives, runny nose, trouble breathing, swelling of the face/throat), severe allergic shock, skin rash
Important Warnings
- Do not use Nexodal if you are allergic to naloxone or any other part of this medicine.
- If you are very used to opioids (painkillers) or have taken large amounts, you might get withdrawal symptoms. These can include high blood pressure, a fast heartbeat, serious trouble breathing, or your heart stopping.
- If Nexodal is given to a baby whose mother used opioids, the baby might have sudden withdrawal symptoms.
- Tell your doctor if you have heart or blood circulation problems. Side effects like high or low blood pressure, fast heartbeat, or serious breathing problems could happen more easily.
- If you are taking buprenorphine for pain, naloxone might not work as well.
Show 2 more warnings
- If you are pregnant, breastfeeding, or planning a baby, ask your doctor for advice before using this medicine. Do not breastfeed for 24 hours after taking this medicine.
- Do not drive or use machines for at least 24 hours after getting Nexodal. The effects of the opioids might come back.