Moxonidin ratiopharm
Moxonidin ratiopharm is a medicine used to lower high blood pressure by acting on the central nervous system.
Form
tabletti, kalvopäällysteinen
Strength
0.4 mg
Active Ingredient
Moxonidine
Manufacturer
Teva B.V.
How to Use
Dosage
Start with 0.2 mg once daily. Your doctor may increase the dose to 0.4 mg once daily after three weeks if needed, or to 0.3 mg twice daily after another three weeks.
Method
Take the tablet with enough liquid (e.g., a glass of water), either before, during, or after a meal.
Important
The maximum single dose is 0.4 mg. The maximum daily dose is 0.6 mg.
Possible Side Effects
COMMON
- •Dry mouth
- •Difficulty thinking clearly
- •Sleep disturbances, drowsiness, feeling foggy, headache, light-headedness, dizziness, insomnia
- •Nausea, vomiting, diarrhea, constipation, indigestion, and other stomach/bowel issues
- •Weakness
- •Widened blood vessels (can appear as mild redness and slight swelling)
- •Back pain
- •Rash, itching
RARE
- •Breast enlargement in men (gynecomastia), impotence, decreased sex drive
- •Depression, anxiety, sleepiness, nervousness, fainting
- •Dry, itchy, burning eyes
- •Ringing in the ears (tinnitus)
- •Neck pain
- •Slow heart rate (bradycardia)
- •Allergic skin reactions, swelling under the skin (angioedema)
- •Difficulty urinating (urinary retention) or inability to control the bladder, causing urine leakage (incontinence)
- •Fluid retention (edema) in various parts of the body
- •Leg weakness
- •Short periods of losing consciousness
- •Loss of appetite
- •Pain in the parotid salivary gland
- •Low blood pressure, dizziness when standing up (orthostatic hypotension), tingling in arms and legs (paresthesia), painful whitening of fingers and toes followed by temporary blue and red color (Raynaud's syndrome), circulation problems in arms and legs.
- •Liver reactions (liver inflammation), cholestasis (blocked bile flow) causing stomach pain, yellow skin/eyes (jaundice), itchy skin.
Important Warnings
- Do not take this medicine if you are allergic to moxonidine or any of its other ingredients.
- Do not take if you have severe heart rhythm problems (like sick sinus syndrome or 2nd/3rd-degree AV block) or a very slow heart rate (below 50 beats per minute).
- Do not take if you have severe heart failure (when your heart cannot pump enough blood, causing shortness of breath and swollen legs).
- Do not take if you have severe kidney problems (especially for the 0.4 mg dose).
- Do not stop taking this medicine suddenly. You should stop it gradually over about two weeks, as your doctor advises.
Show 7 more warnings
- Do not use if you are pregnant or think you might be pregnant.
- Do not use if you are breastfeeding, as the medicine passes into breast milk. If you must take it, you should stop breastfeeding.
- This medicine can cause drowsiness and dizziness, so be careful when driving or operating machines.
- This medicine is not recommended for children and adolescents under 16 years of age.
- Tell your doctor if you have a 1st-degree AV block (a type of heart conduction problem) or severe coronary artery disease (a heart condition causing chest pain).
- Tell your doctor if you have moderate kidney problems; your doctor will regularly check your blood pressure.
- If you are taking beta-blockers, they must be stopped first, and Moxonidin ratiopharm should only be started a few days later to prevent a sharp rise in blood pressure.
Use in Elderly Patients
Category D
Avoid use in older adults. Sedative. Reduce the dose already in mild renal impairment. Significant adverse effects include orthostatism, headache, drowsiness and sleep disorders. Potentiates the effect of CNS depressants. (updated 19.5.2025)