Motifene Dual
Motifene Dual is a medicine that reduces inflammation, pain, and fever.
How to Use
Dosage
The usual dose for adults is one capsule once a day. Your doctor may increase this to one capsule twice a day or two capsules once a day for severe symptoms. The daily dose ranges from 75 mg to 150 mg, depending on how severe your condition is.
Method
Swallow the capsules whole with plenty of liquid. Do not chew them. For sudden pain, take the medicine before a meal, as taking it after a meal can slow down how your body absorbs it.
The maximum recommended daily dose is 150 mg. Do not take more than this unless your doctor tells you to.
Possible Side Effects
- •Headache
- •Dizziness
- •Feeling sick (nausea), vomiting, diarrhea, indigestion, stomach pain, gas, loss of appetite
- •Changes in liver function test results
- •Skin rash
- •Allergic reactions, severe allergic reactions (anaphylaxis)
- •Drowsiness
- •Asthma and shortness of breath
- •Stomach inflammation, bleeding in the stomach or intestines, vomiting blood, bloody or black stools/diarrhea, stomach ulcers
- •Liver inflammation, yellow skin (jaundice), other liver-related disorders
- •Hives
- •Swelling
- •Lack of platelets or white blood cells, anemia, which can lead to increased bruising, nosebleeds, or unexplained infections like sore throat and fever.
- •Swelling of the face, skin, and throat (angioedema).
- •Confusion, depression, sleeplessness, nightmares, irritability, psychotic reactions, memory problems.
- •Tingling (paresthesia), seizures, anxiety, shaking, meningitis without bacteria, changes in taste, brain blood vessel problems.
- •Vision problems, blurred vision, double vision.
- •Ringing in the ears (tinnitus), hearing loss.
- •Palpitations, chest pain, heart failure, heart attack.
- •High blood pressure, inflammation of blood vessels.
- •Lung inflammation.
- •Colon inflammation (including worsening of Crohn's disease or ulcerative colitis), constipation, mouth inflammation, tongue inflammation, esophagus problems, intestinal narrowing, pancreatitis.
- •Severe liver inflammation, liver cell death, liver failure.
- •Blistering skin reactions, eczema, redness, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, peeling skin rash, hair loss, sensitivity to light, purpura (red spots on skin), itching.
- •Acute kidney failure, blood or protein in urine, nephrotic syndrome, interstitial nephritis (a type of kidney inflammation), papillary necrosis in kidneys.
Important Warnings
- Do not use if you are allergic to diclofenac or any other ingredient in this medicine.
- Do not use if other NSAID pain relievers have caused asthma, hives, or a runny nose.
- Do not use if you have stomach or intestinal ulcers, or have had bleeding or perforation in the past from an NSAID.
- Do not use if you have bleeding in the brain or any other active bleeding.
- Do not use if you have severe heart failure.
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- Do not use if you have a known heart or brain circulatory disease (e.g., heart attack, stroke, or TIA), or have had surgery for these.
- Do not use if you have or have had circulation problems in your legs or arms.
- Do not use if you have severe liver or kidney problems.
- Do not use during the last three months of pregnancy.
- Do not use if you are breastfeeding.
- Motifene Dual 75 mg capsules should not be given to children under 12 years of age.
- Using Motifene Dual with other NSAID pain relievers can increase the risk of side effects.
- If you are older, you might be more sensitive to side effects.
- Tell your doctor if you have had a severe skin rash, peeling skin, blisters, or mouth sores after taking Motifene Dual or other pain relievers.
- Motifene Dual can hide the signs of an infection. See a doctor immediately if you notice signs of an infection or if your symptoms worsen.
- Long-term use of Motifene Dual can cause headaches that should not be treated by increasing the dose. Talk to your doctor if this happens.
Use in Elderly Patients
Suitable for older adults, with specific precautions. For short-term use only. Do not use in severe renal impairment. Increases swelling, worsens renal and heart failure and causes cardiovascular events. Increases risk of bleeding, especially in the gastrointestinal tract. Consider potential interactions especially with preparations that increase risk of bleeding. (updated 16.9.2024)