Morphin
Morphin injection is used to treat severe pain, such as after surgery or injury, heart attack, acute pulmonary edema, and chronic pain conditions like cancer pain.
How to Use
Dosage
Typically 4-20 mg (0.2–1 ml) subcutaneously or intramuscularly. For heart attack pain or pulmonary edema, initially 2–8 mg (0.1–0.4 ml) slowly intravenously, then an additional 2–6 mg (0.1–0.3 ml) every 5–15 minutes if needed.
Method
The medicine is usually administered by healthcare professionals subcutaneously, intramuscularly, or intravenously. Administration into the epidural or spinal space is also done by a healthcare professional.
The maximum daily dose for children is 15 mg. For adults, the maximum daily dose is determined by the doctor on a case-by-case basis.
Possible Side Effects
- •Urinary retention (difficulty urinating).
- •Fatigue and drowsiness.
- •Dizziness.
- •Constipation.
- •Nausea.
- •Vomiting.
- •Mood changes (euphoria, anxiety, hallucinations, mood swings, confusion).
- •Breathing depression (slow or shallow breathing).
- •Headache.
- •Sleep disturbances (abnormal dreams, insomnia, restlessness).
- •Seizures and tremors/muscle stiffness.
- •Increased pressure inside the head.
- •Vision problems.
- •Dry mouth.
- •Newborn withdrawal symptoms (if mother used during pregnancy).
- •Heart rate changes (slow or fast heartbeat, palpitations).
- •Blood pressure changes (drop or increase).
- •Skin reactions (redness, itching, rash, hives, injection site reactions, severe skin reactions with blistering and peeling).
- •Anaphylaxis (severe allergic reaction).
- •Pancreatitis, gallbladder issues.
- •Reduced sex hormones (decreased libido, impotence, missed periods).
- •Sleep apnea (breathing stops during sleep), low oxygen levels during sleep.
- •Increased pain sensitivity.
- •Excessive sweating.
- •Paralytic ileus (bowel paralysis).
- •Adrenal insufficiency (weakness, fatigue, loss of appetite, nausea, vomiting, low blood pressure).
Important Warnings
- Do not use if you are allergic to morphine or any other ingredients in this medicine.
- Do not use if you have severe breathing difficulties, asthma attacks, or obstructive lung disease. Morphine can worsen these conditions.
- Do not use if you have gallstones, a bowel obstruction, or paralytic ileus.
- Do not use for pain during childbirth.
- Do not use in the epidural space if you have blood clotting disorders or an infection at the injection site.
Show 6 more warnings
- Tell your doctor if you have had a recent head injury. Morphine can increase pressure inside your head and cause breathing difficulties.
- Tell your doctor if you are using alcohol, sleeping pills, or other medicines that affect your central nervous system, as they can increase the effects of morphine.
- Tell your doctor if you have kidney or liver problems.
- Do not use if you have taken MAO inhibitors in the last 14 days.
- This medicine contains morphine, which can cause addiction. Discuss any concerns with your doctor.
- Do not drive or operate machinery while using this medicine, as it impairs your ability to react and concentrate.
Use in Elderly Patients
Suitable for older adults, with specific precautions. Sedative. Reduce the dose already in mild renal impairment. Avoid use in severe renal impairment. Increases the risk of confusion and falling. Need for laxative is often necessary. (updated 24.3.2025)