Mitomycin Substipharm
Mitomycin is a cancer medicine given into the bladder to help stop bladder cancer from coming back after surgery.
Form
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Strength
20 mg
Active Ingredient
Mitomycin
Manufacturer
Substipharm
How to Use
Dosage
Your doctor will tell you how much medicine to use and how often.
Method
A nurse or doctor will put this medicine directly into your bladder.
Important
Your doctor will decide the maximum amount you can have each day.
Possible Side Effects
COMMON
- •Skin rash, allergic rash, or skin irritation
- •Numbness, swelling, and painful red skin on your palms and soles
- •Bladder swelling (cystitis), which might include blood in your urine or bladder bleeding
- •Pain when you pee, needing to pee often, sometimes at night
- •Blood in your urine
- •Local irritation of the bladder lining
RARE
- •Widespread skin rash
- •Severe bladder inflammation, possibly with dead tissue in parts of the bladder wall
- •Narrowing of the tube that carries urine from the kidney to the bladder (ureter stenosis)
- •Bladder becoming smaller (decreased bladder capacity)
- •Hardening of the bladder wall (calcification, fibrosis)
- •Tear in the bladder wall (bladder perforation)
Important Warnings
- Do not use if you are allergic to mitomycin or any of its ingredients.
- Do not use if you are breastfeeding.
- Do not use if there is a hole in your bladder wall.
- Tell your doctor if you have problems with your lungs, liver, or kidneys.
- Tell your doctor if you are not feeling well overall.
Show 9 more warnings
- Tell your doctor if you are getting radiation therapy.
- Tell your doctor if you are taking other cancer medicines.
- Tell your doctor if you have bladder swelling or infection (cystitis).
- Tell your doctor if you have bone marrow problems (when your body can't make enough blood cells).
- This medicine can affect your ability to have children in the future. Talk to your doctor about family planning.
- The medicine must be put into your bladder very carefully to avoid tearing the bladder wall.
- Do not get any vaccines during this treatment, especially vaccines with live germs.
- Do not use this medicine if you are pregnant.
- This medicine can make you feel sick and throw up, which might make it unsafe to drive or use machines. Alcohol can make this worse.