Mitomycin medac
Mitomycin medac is a cancer medicine that works by stopping or slowing down the growth of cancer cells.
Form
injektio/infuusiokuiva-aine, liuosta varten
Strength
1 mg/ml
Active Ingredient
Mitomycin
Manufacturer
Medac Gesellschaft Für Klinische Spezialpräparate mbH
How to Use
Dosage
Your doctor will decide your dose and how often you get it. For IV use, doses range from 5–20 mg per square meter of body surface every 3–8 weeks. For bladder use, it's usually 40 mg once a week.
Method
This medicine is given as an injection or infusion into a vein, or through a catheter into the bladder.
Important
The maximum daily dose will be determined by your doctor, as typical doses are given weekly or less often.
Possible Side Effects
COMMON
- •Feeling sick to your stomach (nausea) and throwing up (vomiting)
- •Lower number of white blood cells (makes infections more likely)
- •Lower number of platelets (can cause bruising and bleeding)
- •Problems with your kidneys (you might pee less or not at all)
- •Rashes on your skin, including allergic rashes or redness from touching the medicine
- •Numbness, swelling, and redness in your hands and feet
- •Shortness of breath, dry cough, or wheezing
- •Inflammation of the bladder (cystitis), sometimes with blood in your pee
- •Pain when you pee
- •Needing to pee more often, especially at night
- •Blood in your pee
- •Local irritation in the bladder
- •Local skin rash
RARE
- •Inflammation or tissue death if the medicine leaks outside the vein
- •Soreness in the lining of your mouth or other body openings
- •Diarrhea
- •Hair loss
- •Fever
- •Loss of appetite
- •Serious infection that could be life-threatening, or blood poisoning
- •Low red blood cells due to them breaking down too fast (hemolytic anemia)
- •Bruising or purple spots on the skin due to bleeding under the skin
- •Heart problems
- •High blood pressure in the lungs or blocked lung blood vessels
- •Liver problems, including yellow skin or eyes
- •Rash all over the body
- •A serious kidney problem called HUS (hemolytic uremic syndrome)
- •Severe allergic reactions (like dizziness, hives, itching, swelling of your face, lips, or throat, trouble breathing, or passing out)
- •Bladder inflammation with tissue damage or allergic bladder inflammation
- •Narrowing of the tubes that carry pee from your body
- •Smaller bladder size
- •Calcium buildup or fibrous tissue in the bladder wall
Important Warnings
- Do not use if you are allergic to mitomycin or any of its ingredients.
- Do not breastfeed during treatment.
- If given into a vein, do not use if you have too few blood cells, a tendency to bleed easily, or an active infection.
- If given into the bladder, do not use if your bladder wall is torn or if you have a bladder infection.
- Tell your doctor if you are generally unwell, have lung, liver, or kidney problems, or are receiving radiation or other cancer treatments.
Show 4 more warnings
- Inform your doctor if you have bone marrow depression (your body makes too few blood cells) or if you are pregnant, planning pregnancy, or can become pregnant, as this medicine can harm an unborn baby and affect your ability to have children.
- Avoid the medicine touching your skin or other sensitive body parts.
- Do not get live vaccines during treatment.
- This medicine may make you feel sick or vomit, which can make it unsafe to drive or use machines.