Mirtazapin Sandoz
Mirtazapin Sandoz is an antidepressant medication used to treat depression in adults.
Form
tabletti, kalvopäällysteinen
Strength
45 mg
Active Ingredient
Mirtazapine
Manufacturer
Sandoz A/S
How to Use
Dosage
Your doctor will tell you the right dose. It usually starts at 15 or 30 mg daily and can be increased to 15-45 mg daily.
Method
Take your tablet at the same time each day, usually once before bedtime. Your doctor might suggest taking it twice a day (morning and evening). Swallow the tablet whole with water or juice; do not chew it.
Important
The maximum daily dose is 45 mg.
Possible Side Effects
COMMON
- •Increased appetite and weight gain
- •Drowsiness or sleepiness
- •Headache
- •Dry mouth
- •Dizziness
- •Tremor or shaking
- •Feeling sick (nausea), diarrhea, vomiting, or constipation
- •Skin rash or eczema
- •Joint or muscle pain
- •Back pain
- •Dizziness or fainting when standing up quickly
- •Swelling (usually ankles or feet) due to fluid retention
- •Vivid dreams
- •Confusion
- •Anxiety
- •Sleep problems
- •Memory problems (usually go away when treatment is stopped)
RARE
- •Unusual skin sensations (burning, tingling, itching)
- •Restless legs
- •Fainting
- •Numbness in the mouth
- •Low blood pressure
- •Nightmares
- •Anxiety with strong need to move
- •Hallucinations
- •Involuntary movements
- •Muscle twitching or spasms
- •Aggressiveness
- •Abdominal pain and nausea (may be signs of pancreas inflammation)
- •Swelling of the mouth or entire body
- •Low sodium levels in the blood
- •Inappropriate release of antidiuretic hormone
- •Severe skin reactions (like blistering rash or widespread red rash)
- •Sleepwalking
- •Speech problems
- •Increased creatinine kinase levels in the blood
- •Difficulty urinating
- •Muscle pain, stiffness, weakness, or dark/discolored urine (signs of rhabdomyolysis)
- •High prolactin levels in the blood (with symptoms like breast milk discharge or enlarged breasts in men)
- •Painful prolonged erection
Important Warnings
- Do not take this medicine if you are allergic to mirtazapine or any other ingredients.
- Do not take Mirtazapin Sandoz if you are currently taking or have recently taken (in the last two weeks) other medicines called MAO inhibitors (MAOIs). Also, do not take MAOIs for two weeks after stopping Mirtazapin Sandoz.
- Be careful if you take Mirtazapin Sandoz with other antidepressants (like SSRIs, venlafaxine, L-tryptophan), triptans for migraines, buprenorphine, tramadol, linezolid, lithium, methylene blue, or St. John's wort. This combination can cause 'serotonin syndrome,' with symptoms like high fever, sweating, fast heartbeat, diarrhea, muscle twitching, restlessness, and confusion. If you get these symptoms, contact your doctor right away.
- If you are pregnant, think you might be pregnant, or are breastfeeding, talk to your doctor before taking this medicine.
- Mirtazapin Sandoz can make you less alert. Do not drive or operate machinery until you know how this medicine affects you.
Show 5 more warnings
- Do not drink alcohol while taking Mirtazapin Sandoz, as it can make you sleepy.
- Do not stop taking Mirtazapin Sandoz suddenly. Always talk to your doctor first. Stopping suddenly can cause withdrawal symptoms like feeling sick, dizzy, restless, anxious, or having headaches. Your doctor will help you reduce the dose slowly.
- If you experience any severe side effects like extreme high mood (mania), yellowing of eyes or skin (jaundice), signs of infection (sudden fever, sore throat, mouth sores), seizures, symptoms of serotonin syndrome (fever, sweating, fast heart rate, diarrhea, muscle twitching, confusion), thoughts of harming yourself, or severe skin reactions (red spots, blistering, peeling skin, fever, swollen lymph nodes), stop taking the medicine and contact your doctor right away.
- Tell your doctor if you have or have had seizures (epilepsy), liver or kidney disease, heart problems (like low blood pressure, rhythm issues, recent heart attack, or heart failure), schizophrenia, manic depression (bipolar disorder), diabetes, eye conditions (like glaucoma), difficulty urinating, or signs of infection (like fever or sore throat).
- Elderly patients may be more sensitive to side effects.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Sedative. Suitable in low doses (3. Reduce the dose in moderately severe renal impairment. Increases risk of falls. May cause low serum sodium level. (updated 12.2.2024)