Mirtazapin Krka

Mirtazapin Krka is a medicine used to treat depression.

Form
tabletti, kalvopäällysteinen
Strength
30 mg
Active Ingredient
Mirtazapine
Manufacturer
KRKA d.d. Novo mesto

How to Use

Dosage

The usual starting dose is 15-30 mg once a day. Your doctor may increase it to 15-45 mg per day.

Method

Take Mirtazapin Krka tablets at the same time each day. It's best to take a single dose just before bedtime. Your doctor might suggest taking one dose in the morning and one in the evening. Swallow the tablets whole with water or juice.

Important

The maximum daily dose is 45 mg.

Possible Side Effects

COMMON
  • Increased appetite and weight gain
  • Tiredness and sleepiness
  • Headache
  • Dry mouth
  • Drowsiness (lethargy)
  • Dizziness
  • Trembling or shaking
  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Rash or skin problems
  • Joint pain or muscle pain
  • Back pain
  • Dizziness or fainting when standing up too quickly
  • Swelling due to fluid retention (especially ankles or feet)
  • Vivid dreams
  • Confusion
  • Anxiety
  • Sleep problems
  • Memory problems, which usually went away after stopping the medicine
RARE
  • Excessive high mood (mania)
  • Yellowing of the eyes or skin (jaundice), which can be a sign of liver problems
  • Abnormal skin sensations, like burning, tingling, or itching
  • Restless legs
  • Fainting
  • Numbness in the mouth
  • Low blood pressure
  • Nightmares
  • Feeling anxious with a strong need to move
  • Hallucinations
  • Compulsive need to move
  • Muscle twitching or spasms
  • Aggressiveness
  • Stomach pains and nausea, possibly a sign of pancreas inflammation
  • Signs of infection like sudden high fever, sore throat, or mouth sores (agranulocytosis). In rare cases, mirtazapine can affect blood cell production.
  • Epileptic attacks (seizures)
  • A combination of symptoms like unexplained fever, sweating, fast heartbeat, diarrhea, muscle contractions, shivering, overactive reflexes, restlessness, mood changes, unconsciousness, and increased saliva (serotonin syndrome).
  • Thoughts of harming yourself or suicide
  • Severe skin reactions: red target-like spots or rings on the body, often with blisters; peeling skin; sores in the mouth, throat, nose, genitals, and eyes. These can be preceded by fever and flu-like symptoms (Stevens-Johnson syndrome, toxic epidermal necrolysis) or widespread rash, fever, and swollen lymph nodes (DRESS).

Important Warnings

  • Do not use if you are allergic to mirtazapine or any other ingredients.
  • Do not use if you are taking or have recently taken (within the last two weeks) medicines called MAO inhibitors.
  • If you get a severe rash, peeling skin, or sores, tell your doctor right away.
  • This medicine is generally not for children and teenagers under 18 years old.
  • If you have thoughts of harming yourself or suicide, contact your doctor or go to a hospital right away.
Show 5 more warnings
  • If you have signs of infection, such as high fever or sore throat, contact your doctor right away.
  • Avoid drinking alcohol with this medicine.
  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • This medicine can affect your concentration. Do not drive or use machines until you know how it affects you.
  • Do not stop taking this medicine suddenly without talking to your doctor.

Use in Elderly Patients

Category C

Suitable for older adults, with specific precautions. Sedative. Suitable in low doses (3. Reduce the dose in moderately severe renal impairment. Increases risk of falls. May cause low serum sodium level. (updated 12.2.2024)