Mirtazapin Hexal
Mirtazapin Hexal is an antidepressant medicine used to treat depression in adults.
Form
tabletti, kalvopäällysteinen
Strength
15 mg
Active Ingredient
Mirtazapine
Manufacturer
Hexal A/S
How to Use
Dosage
The starting dose is usually 15 or 30 mg per day, and your doctor may increase it to 15–45 mg per day.
Method
Take this medicine at the same time each day, usually as a single dose right before bedtime, or your doctor may suggest splitting the dose into morning and evening, with the larger dose before bedtime. Swallow the tablet whole with water or juice, with or without food.
Important
The maximum daily dose is 45 mg.
Possible Side Effects
COMMON
- •Increased appetite and weight gain
- •Drowsiness and sleepiness
- •Headache
- •Dry mouth
- •Lethargy
- •Dizziness
- •Tremor
- •Nausea
- •Diarrhea
- •Vomiting
- •Constipation
- •Skin rash
- •Joint or muscle pain
- •Back pain
- •Dizziness or fainting when standing up quickly (orthostatic hypotension)
- •Swelling due to fluid retention (e.g., ankles or feet)
- •Vivid dreams
- •Confusion
- •Anxiety
- •Insomnia
- •Memory problems (usually went away after stopping treatment)
RARE
- •Excessively high mood (mania)
- •Abnormal skin sensations (e.g., burning, stinging, itching, or tingling)
- •Restless legs
- •Fainting
- •Numb mouth
- •Low blood pressure
- •Nightmares
- •Anxiety with a strong urge to move
- •Hallucinations
- •Strong urge to move
- •Yellowing of the eyes or skin (sign of liver problem, jaundice)
- •Muscle twitches or contractions
- •Aggression
- •Stomach pain and nausea (may be a symptom of pancreatitis)
- •Signs of infection (e.g., sudden high fever, sore throat, mouth sores) due to blood cell issues
- •Epileptic seizures
- •Serotonin syndrome (a group of symptoms like unexplained fever, sweating, fast heart rate, diarrhea, muscle spasms, mood changes, and unconsciousness)
- •Thoughts of self-harm or suicide
- •Severe skin reactions (e.g., red spots on the body like targets, peeling skin, sores in mouth, throat, nose, genitals, and eyes – Stevens-Johnson syndrome, toxic epidermal necrolysis; widespread rash, high fever, enlarged lymph nodes – DRESS syndrome)
- •Abnormal sensations in the mouth (oral paresthesia)
- •Mouth swelling (oral edema)
- •Whole body swelling (generalized edema)
- •Local swelling
- •Low sodium in blood (hyponatremia)
- •Inappropriate antidiuretic hormone secretion
- •Sleepwalking
- •Speech problems
- •Increased blood creatine kinase levels
- •Difficulty passing urine (urinary retention)
- •Muscle pain, stiffness and/or weakness, and dark or discolored urine (rhabdomyolysis)
- •Unusually high prolactin levels in blood (hyperprolactinemia, including breast milk production and enlarged breasts in men)
- •Prolonged painful erection of the penis
Important Warnings
- Do not use if you are allergic to mirtazapine or its ingredients, or if you are taking or have taken MAO inhibitors within the last two weeks.
- If you have had severe skin reactions (like rash, blistering, or peeling skin) with Mirtazapin Hexal, stop use and see a doctor right away.
- Tell your doctor if you have thoughts of self-harm or suicide, especially if you are under 25 years old.
- Talk to your doctor if you have or have had seizures, liver or kidney disease, heart disease, schizophrenia, bipolar disorder, diabetes, high eye pressure (glaucoma), or difficulty urinating.
- If you get signs of infection (like unexplained fever, sore throat, or mouth sores), stop Mirtazapin Hexal and contact your doctor immediately for blood tests.
Show 3 more warnings
- Do not drink alcohol while taking this medicine.
- Talk to your doctor before use if you are pregnant, breastfeeding, or planning to become pregnant.
- Be careful when driving or using machines, as this medicine can make you less alert.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Sedative. Suitable in low doses (3. Reduce the dose in moderately severe renal impairment. Increases risk of falls. May cause low serum sodium level. (updated 12.2.2024)