Minirin
Minirin works like a natural hormone to help your kidneys concentrate urine, treating conditions like central diabetes insipidus, bedwetting, and frequent nighttime urination.
How to Use
Dosage
For diabetes insipidus, adults and children take 1-2 tablets (60 mcg) under the tongue three times a day. For children's bedwetting, take 1-2 tablets (120 mcg) under the tongue at night. For adults with frequent nighttime urination, start with 60 mcg under the tongue at night and can increase up to 240 mcg weekly if needed.
Method
Place the freeze-dried, melt-in-the-mouth tablet under your tongue.
The maximum dose depends on the condition being treated, but do not exceed 240 micrograms per day.
Possible Side Effects
- •Headache
- •Low blood sodium (hyponatremia)
- •Dizziness
- •High blood pressure
- •Nausea
- •Stomach pain
- •Diarrhea
- •Constipation
- •Vomiting
- •Bladder and urethra problems
- •Swelling
- •Tiredness
- •Mood changes
- •Aggression
- •Anxiety
- •Nightmares
- •Drowsiness
- •Irritability
- •Severe allergic reaction (anaphylaxis)
- •Unusual behavior
- •Emotional problems
- •Depression
- •Seeing things that aren't there (visual hallucination)
- •Trouble sleeping (insomnia)
- •Trouble paying attention
- •Being overly active (psychomotor hyperactivity)
- •Seizures (convulsions)
- •Nosebleeds
- •Allergic skin rash
- •Rash
- •Sweating
- •Hives
- •Strange sensations
- •Blurred vision
- •Spinning sensation (vertigo)
- •Heart palpitations
- •Dizziness when standing up
- •Shortness of breath
- •Digestion problems
- •Gas and bloating
- •Itching
- •Muscle cramps
- •Muscle pain
- •Feeling unwell (malaise)
- •Chest pain
- •Flu-like illness
- •Weight gain
- •Increased liver enzymes
- •Low blood potassium (hypokalemia)
- •Confusion
- •Dehydration
- •High blood sodium (hypernatremia)
- •Extreme weakness
- •Coma
Important Warnings
- Limit fluid intake 1 hour before and 8 hours after taking Minirin; only drink enough to quench your thirst.
- Do not use this medicine if you are allergic to desmopressin or any other ingredients.
- Do not use if you drink too much fluid (polydipsia), have heart failure, or other conditions requiring water pills.
- Do not use if you have poor kidney function or low sodium levels in your blood.
- Be careful if you have an acute illness that might affect your body's fluid balance.
Show 2 more warnings
- Be careful if you are 65 or older and have low sodium levels in your blood or pass a lot of urine daily.
- Tell your doctor about all other medicines you are taking, as some can make Minirin work stronger.
Use in Elderly Patients
Avoid use in older adults. Risk of fluid retention and hyponatraemia. Treatment of ADH deficiency can be started under specialist supervision. (updated 6.11.2023)