Milnocor
Milnocor is a medicine that helps your heart pump more effectively and widens blood vessels.
Form
injektio-/infuusioneste, liuos
Strength
1 mg/ml
Active Ingredient
Milrinone
Manufacturer
Macure Pharma ApS
How to Use
Dosage
Your doctor will decide the dose; typically, a starting dose of 50 micrograms of milrinone per kg of body weight over 10 minutes is given, followed by a continuous infusion of 0.375–0.75 micrograms per kg per minute.
Method
The medicine is given as a slow injection or infusion directly into a vein.
Important
The maximum daily dose is 1.13 mg of milrinone per kg of body weight.
Possible Side Effects
COMMON
- •Mild to moderate headache
- •Irregular heartbeat due to extra beats
- •Fast heartbeat
- •Heart rhythm disorders
- •Low blood pressure
RARE
- •Decreased platelet count
- •Low potassium level
- •Tremor
- •Ventricular fibrillation (a serious irregular heartbeat)
- •Severe chest pain, often with a tight feeling and shortness of breath
- •Elevated liver enzymes (signs of liver problems)
- •Decreased red blood cell count
- •Decreased hemoglobin level
- •Severe allergic reaction (anaphylactic shock)
- •Dangerous fast heartbeat (Torsade de Pointes)
- •Spasms of the airways (bronchospasm)
- •Skin reactions, such as rash
- •Reactions at the infusion site
- •Bleeding around the brain (intraventricular hemorrhage) (in children)
- •Heart defect called patent ductus arteriosus (an open connection between two major blood vessels) (in children)
Important Warnings
- Do not use Milnocor if you are allergic to milrinone or any other ingredient.
- Tell your doctor if you have severe narrowing of your heart valves.
- Milnocor can make some heart rhythm problems worse, so tell your doctor if you have a history of them.
- Your doctor will check if your heart's filling pressure is too low and fix it before you get Milnocor.
- Tell your doctor if you have kidney problems or low blood pressure.
Show 3 more warnings
- Milnocor might lower your blood platelet or red blood cell counts, so your doctor will watch these levels closely.
- The injection site must be closely watched to prevent problems.
- Treatment with Milnocor should not last longer than 48 hours.