Midive
Midive widens blood vessels from the heart to the lungs, which helps improve your ability to be physically active.
Form
tabletti, kalvopäällysteinen
Strength
2.5 mg
Active Ingredient
Riociguat
Manufacturer
Adalvo Limited
How to Use
Dosage
The recommended starting dose is one 1 mg tablet, three times a day, for two weeks.
Method
Take tablets three times a day, every 6-8 hours, with or without food. If you have trouble swallowing, tablets can be crushed and mixed with water or soft food like applesauce.
Important
The maximum daily dose is 7.5 mg (three 2.5 mg tablets).
Possible Side Effects
COMMON
- •Headache
- •Dizziness
- •Indigestion or upset stomach after meals
- •Swelling of arms and legs
- •Diarrhea
- •Nausea or vomiting
- •Stomach inflammation (gastritis)
- •Stomach and gut inflammation (gastroenteritis)
- •Anemia (low red blood cells, causing pale skin, weakness, or shortness of breath)
- •Palpitations (fast or irregular heartbeat)
- •Low blood pressure
- •Nosebleed
- •Nasal congestion (stuffy nose)
- •Abdominal pain (stomach, gut, or belly pain)
- •Heartburn or reflux
- •Difficulty swallowing
- •Constipation
- •Bloating (swollen belly)
- •Coughing up blood
RARE
- •Sudden bleeding in the lungs
Important Warnings
- Do not take Midive if you are allergic to riociguat or any other ingredient in this medicine.
- Do not take Midive if you are pregnant or planning to become pregnant; take monthly pregnancy tests during treatment.
- Do not take Midive if you are taking PDE5 inhibitors (e.g., sildenafil), nitrates, nitric oxide donors (e.g., amyl nitrite), or other soluble guanylate cyclase stimulators (e.g., vericiguat).
- Tell your doctor if you have severe liver disease, or if you are on dialysis or your kidneys do not work well.
- Tell your doctor if you have low blood pressure or symptoms like dizziness, weakness, or fainting.
Show 2 more warnings
- Tell your doctor if you recently had severe lung bleeding, have been treated for coughing up blood, or are taking blood thinners.
- Tell your doctor if you start or stop smoking during treatment, as your dose may need adjustment.