Midazolam Accord
Midazolam Accord is a fast-acting medicine used to make you calm, relaxed, and less anxious for medical procedures or during intensive care.
How to Use
Dosage
Your doctor or nurse will determine the correct dose for you based on your treatment needs, weight, age, and other medical factors. You will not administer this medicine yourself.
Method
This medicine is given as an injection into a vein (intravenous) or muscle, or it can be given rectally. It is always administered by a healthcare professional.
The maximum daily dose will be decided by your doctor or nurse, as the dosage is carefully controlled by healthcare professionals to ensure your safety.
Possible Side Effects
- •Anaphylactic shock (a very serious allergic reaction): symptoms may include a sudden rash, itching, swelling of the face, lips, tongue, or other body parts, trouble breathing or wheezing, pale skin, a weak and fast pulse, chest pain, or feeling like you might pass out. Seek immediate medical help.
- •Heart attack: symptoms can include chest pain that may spread to your neck, shoulders, and left arm.
- •Severe breathing problems: these can sometimes lead to breathing stopping, choking, or a sudden blockage of your airway.
- •Allergic reactions (e.g., skin rash, wheezing, heart and blood circulation problems).
- •Restlessness, agitation, irritability, anxiety, anger, aggression, hyperactivity, changes in sex drive, inappropriate behavior.
- •Confusion, disorientation (not knowing where you are), mood changes, involuntary movements, nightmares, unusual dreams, seeing or hearing things that aren't there (hallucinations), severe mental problems (psychosis), drowsiness, prolonged sedation (very sleepy for a long time), poor concentration, headache, dizziness, problems coordinating movements, seizures (in premature babies and newborns), temporary memory loss (how long depends on the dose you received), drug dependence or misuse, nervousness, muscle spasms or tremors.
- •Low blood pressure (can make you feel dizzy or faint), slow heart rate, flushed face or neck, fainting.
- •Shortness of breath, hiccups.
- •Feeling sick (nausea) or vomiting, constipation, dry mouth.
- •Skin rash, hives (itchy raised spots), itching.
- •Muscle spasms, involuntary muscle tremors (uncontrolled shaking).
- •Redness, swelling, blood clots, or pain at the injection site.
- •Tiredness, fatigue.
- •Increased risk of falls and bone fractures, especially in older people or when taken with other calming medicines (including alcohol).
Important Warnings
- Do not take this medicine if you are allergic to midazolam, any other ingredients in this medicine, or other similar medicines called benzodiazepines (like diazepam or nitrazepam).
- Do not take this medicine for sedation if you have severe breathing problems, as it can make them worse.
- Avoid drinking alcohol while receiving this medicine. Alcohol can make the medicine's calming effects stronger and cause serious breathing problems.
- This medicine can make you drowsy, dizzy, or cause memory problems. Do not drive or use machines until you have fully recovered and your doctor has told you it is safe.
- Do not breastfeed for 24 hours after receiving this medicine, as it can pass into breast milk. Tell your doctor if you are pregnant, think you might be pregnant, or are planning to become pregnant.
Use in Elderly Patients
Avoid use in older adults. Sedative. Being very short-acting, may cause amnesia and confusion. Increases the risk of drug addiction, rebound insomnia and cognitive disorder. Increases the risk of falls and traffic accidents. Paradoxically, may increase anxiety, restlessness and aggression. Consider the numerous potential interactions. Avoid grapefruit. (updated 12.2.2024)