Methotrexat Accord
Methotrexat Accord contains methotrexate, a medicine that stops cell growth and weakens your immune system.
Form
tabletti
Strength
2.5 mg
Active Ingredient
Methotrexate
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
Your doctor will tell you the exact dose; for many conditions, it's usually between 7.5 and 15 mg.
Method
Take the tablet by mouth with some water, once a week, on the same day each week, with or without food, as your doctor tells you.
Important
Do not take this medicine more than once a week. Taking too much can be very dangerous or even deadly.
Possible Side Effects
COMMON
- •Loss of appetite, nausea, vomiting, stomach pain, indigestion
- •Sores or inflammation in the mouth and throat
- •Higher liver enzyme levels (seen in blood tests)
- •Infections
- •Fewer blood cells (which can cause anemia or increase infection risk)
- •Headache, tiredness, dizziness
- •Lung problems (like inflammation, dry cough, shortness of breath, and fever)
- •Diarrhea
- •Skin rash, redness, itching
RARE
- •Swollen lymph nodes (lymphoma)
- •Severe allergic reactions
- •Diabetes, depression
- •Confusion, seizures, or nerve problems (like muscle weakness, changes in taste or sensation, paralysis, speech problems, or brain swelling)
- •Lung damage or fluid in the lungs
- •Bleeding in the stomach or gut, bloody stools, or vomiting blood
- •Liver damage or failure
- •Skin problems like hives, increased sun sensitivity, hair loss, shingles, slow wound healing, nail infections, acne, or red/purple spots on the skin
- •Joint or muscle pain, weak bones (osteoporosis)
- •Kidney problems (like painful or reduced urination, or kidney failure)
- •Vaginal inflammation or sores, fertility issues (like reduced sperm production or erectile problems)
- •Heart sac inflammation, low blood pressure, blood clots
- •Tonsillitis, asthma, or breathing stops
- •Pancreatitis or gum inflammation
- •Severe vision problems, red eyes, or retinal damage
- •Swollen glands, fever, general weakness
- •Bleeding from the lungs
Important Warnings
- Do not take if you are allergic to methotrexate or any other ingredients in this medicine.
- Do not take if you have severe kidney, liver, or blood problems (like severe anemia).
- Do not drink a lot of alcohol while taking this medicine.
- Tell your doctor if you have a weak immune system or a serious infection (like tuberculosis or HIV).
- Tell your doctor if you have stomach ulcers or mouth sores.
Show 8 more warnings
- Do not take if you are pregnant, planning to become pregnant, or breastfeeding (unless for cancer treatment), as this medicine can harm an unborn baby.
- Avoid live vaccines while taking this medicine or shortly before/after.
- This medicine can make your skin more sensitive to the sun. Avoid strong sunlight and tanning beds.
- If you get severe diarrhea, tell your doctor, as treatment might need to be stopped.
- This medicine can make you tired or dizzy. Do not drive or operate machines if you feel this way.
- If you have a sugar intolerance (lactose intolerance), talk to your doctor before taking this medicine.
- Men should avoid getting a woman pregnant or donating sperm during treatment and for at least 3 months after stopping this medicine.
- Contact your doctor immediately if you or your caregiver notice new or worsening neurological symptoms like muscle weakness, vision changes, or confusion.