Metforem
Metforem helps lower high blood sugar by reducing sugar production in the liver and improving its use in the body.
Form
depottabletti
Strength
500 mg
Active Ingredient
Metformin hydrochloride
Manufacturer
Orion Corporation
How to Use
Dosage
The usual starting dose is 500 mg once a day.
Method
Take the tablets whole with water, usually once a day with your evening meal. Your doctor may sometimes recommend taking them twice a day.
Important
The maximum daily dose is 2000 mg.
Possible Side Effects
COMMON
- •diarrhea
- •vomiting
- •nausea
- •stomach pain
- •loss of appetite
- •taste disturbance (metallic taste in mouth)
- •low vitamin B12 levels
RARE
- •lactic acidosis (a serious medical emergency)
- •abnormal liver function tests, liver inflammation (these usually resolve after stopping Metforem)
- •skin reactions (e.g., redness, itching, hives)
Important Warnings
- Do not take Metforem if you are allergic to metformin or any other ingredient in this medicine.
- Do not take Metforem if you have severe kidney problems.
- Do not take Metforem if your diabetes is poorly controlled (e.g., very high blood sugar, nausea, vomiting, rapid weight loss) or if you have ketoacidosis or lactic acidosis. Lactic acidosis is a serious condition that can lead to coma.
- Stop taking Metforem temporarily if you are severely dehydrated (e.g., from severe vomiting, diarrhea, fever, or not drinking enough fluids).
- Do not take Metforem if you have severe liver, heart, or lung disease.
Show 3 more warnings
- Avoid excessive alcohol consumption while taking Metforem as it increases the risk of lactic acidosis.
- Stop taking Metforem before major surgery or imaging tests with iodine contrast. Your doctor will tell you when to stop and restart.
- If you are 75 years or older, you should not start Metforem for type 2 diabetes prevention.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Reduce the dose already in mild renal impairment. Do not use in severe renal impairment or tissue hypoxia. May reduce the absorption of vitamin B12. Consider risk of lactic acidosis. The drug should be paused during fever, gastroenteritis or dehydration, and before surgery or imaging with a contrast agent. (updated 20.5.2024)