Mecastrin

Mecastrin is a medicine containing melatonin, a natural hormone, used for short-term treatment of primary insomnia in people 55 years and older.

Form
depottabletti
Strength
2 mg
Active Ingredient
Melatonin
Manufacturer
Orifarm Generics A/S

How to Use

Dosage

Take one Mecastrin 2 mg tablet once a day.

Method

Take it after food, 1-2 hours before you go to bed. Swallow the tablet whole; do not crush or split it.

Important

Do not take more than one tablet (2 mg) per day. Treatment can last up to 13 weeks.

Possible Side Effects

COMMON
  • •Chest pain
  • •Irritability
  • •Nervousness
  • •Restlessness
  • •Insomnia (trouble sleeping)
  • •Abnormal dreams
  • •Nightmares
  • •Anxiety
  • •Migraine
  • •Headache
  • •Lethargy (feeling tired, lack of energy)
  • •Restlessness with increased activity
  • •Dizziness
  • •Drowsiness (sleepiness)
  • •High blood pressure
  • •Upper stomach pain
  • •Indigestion or stomach upset
  • •Mouth ulcers
  • •Dry mouth
  • •Nausea (feeling sick)
  • •Changes in blood tests that might make your skin or eyes look yellow
  • •Skin inflammation
  • •Night sweats
  • •Itching
  • •Rash
  • •Dry skin
  • •Pain in arms and legs
  • •Menopausal symptoms
  • •Feeling of weakness
  • •Sugar in urine
  • •Too much protein in urine
  • •Abnormal liver function
  • •Weight gain
RARE
  • •Unconsciousness or fainting
  • •Severe chest pain due to angina
  • •Palpitations (fast or irregular heartbeat)
  • •Depression
  • •Blurred vision or decreased sharpness of vision
  • •Confusion or not knowing where you are
  • •Dizziness or spinning sensation (vertigo)
  • •Red blood cells in urine
  • •Low white blood cell count
  • •Low platelet count, which increases risk of bleeding or bruising
  • •Psoriasis (a skin condition)
  • •Shingles (herpes zoster)
  • •High blood fat levels
  • •Low blood calcium levels
  • •Low blood sodium levels
  • •Mood changes
  • •Aggression
  • •Agitation
  • •Crying spells
  • •Stress symptoms
  • •Waking up too early in the morning
  • •Increased sexual desire
  • •Low mood
  • •Memory problems
  • •Trouble paying attention
  • •Feeling like you're in a dream
  • •Restless legs syndrome
  • •Poor sleep quality
  • •Tingling or numbness
  • •More tears or watery eyes
  • •Dizziness when standing up or sitting down
  • •Hot flashes
  • •Acid reflux or heartburn
  • •Stomach or gut problems
  • •Blisters in the mouth
  • •Sores on the tongue
  • •Stomach discomfort
  • •Vomiting
  • •Unusual bowel sounds
  • •Gas or bloating
  • •Too much saliva
  • •Bad breath
  • •Inflammation of the stomach lining
  • •Redness of the skin
  • •Skin rash on hands
  • •Itchy rash
  • •Nail problems
  • •Joint inflammation (arthritis)
  • •Muscle cramps or spasms
  • •Neck pain
  • •Night cramps
  • •A long-lasting, sometimes painful erection (priapism)
  • •Prostate gland inflammation
  • •Fatigue
  • •Pain
  • •Thirst
  • •Urinating a lot
  • •Urinating at night
  • •High liver enzyme levels in blood
  • •Abnormal blood salt levels and unusual lab test results

Important Warnings

  • Do not use if you are allergic to melatonin or any other ingredient in this medicine.
  • If you have liver or kidney problems, talk to your doctor before taking Mecastrin.
  • If your doctor has told you that you have sugar intolerance, talk to your doctor before taking this medicine.
  • If you have an autoimmune disease (when your body's immune system attacks itself), talk to your doctor before taking Mecastrin.
  • This medicine can make you sleepy. Do not drive or use machines if you feel sleepy.
Show 4 more warnings
  • Smoking can make Mecastrin less effective.
  • Do not give this medicine to children or teenagers under 18 years old.
  • Do not use Mecastrin if you are pregnant, breastfeeding, planning to get pregnant, or think you might be pregnant. Ask your doctor or pharmacist for advice.
  • Do not drink alcohol before, during, or after taking Mecastrin, as it can make the medicine less effective.

Use in Elderly Patients

Category A

Suitable for older adults. Has fewer adverse effects than benzodiazepines andrelated drugs. Non-pharmacological methods are the first-line treatment for insomnia. (updated 18.3.2024)