Madopar
Madopar is a medicine that helps manage the symptoms of Parkinson's disease by increasing a brain chemical called dopamine.
Form
tabletti
Strength
200 mg / 50 mg
Active Ingredient
Levodopa
Manufacturer
Roche Oy
How to Use
Dosage
Your doctor will tell you exactly how much Madopar to take; doses vary and are usually started small and increased gradually.
Method
Take 30 minutes before a meal or one hour after. Tablets can be swallowed whole, split, crushed, or chewed. Swallow capsules whole with liquid. Quick tablets should be dissolved in half a glass of water and drunk within 30 minutes.
Important
Your doctor will determine your maximum daily dose.
Possible Side Effects
COMMON
- •Changes in blood test results
- •Decreased appetite
- •Depression
- •Agitation (restless movements)
- •Anxiety
- •Insomnia (trouble sleeping)
- •Increased drowsiness
- •Hallucinations
- •Delusions
- •Confusion
- •Disorientation (difficulty knowing time and place)
- •Dopamine dysregulation syndrome (overuse of medicine)
- •Involuntary movements
- •Sudden changes in your ability to move
- •Loss or change of taste
- •Irregular heartbeat
- •Dizziness when standing up quickly
- •Nausea
- •Vomiting
- •Diarrhea
- •Discolored saliva, tongue, teeth, or mouth lining
- •Liver changes detected by laboratory tests
- •Itching
- •Rash
- •Restless legs
- •Discolored urine
- •Increased urea in blood
- •Strong urges to gamble
- •Overeating (eating large amounts of food quickly or more than needed)
- •Overspending (uncontrolled and excessive shopping/spending)
- •Increased sexual interest or behavior
RARE
- •Temporary sudden sleep attacks during the daytime
Important Warnings
- Do not take Madopar if you are allergic to levodopa, benserazide, or any other ingredients in this medicine.
- Do not take if you have severe kidney, liver, or heart problems.
- Do not take if you have a severe endocrine disease (e.g., overactive thyroid) or certain mental illnesses.
- Do not take if you have narrow-angle glaucoma (high eye pressure).
- Do not take if you are under 25 years old.
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- Do not take if you are pregnant or breastfeeding.
- Do not take if you are taking a combination of MAO-A and MAO-B inhibitors.
- If you are allergic to peanuts or soy, do not use Madopar depot capsules.
- Tell your doctor if you have open-angle glaucoma, stomach ulcers, or bone softening disease.
- Tell your doctor if you have had malignant melanoma (skin cancer).
- Tell your doctor if you are going to have surgery.
- This medicine can cause you to have strong urges to do things that could be harmful, like gambling, overeating, or increased sexual interest. Tell your doctor if this happens.
- This medicine can make you feel sleepy or suddenly fall asleep. Do not drive or operate machines if this happens.
- Do not stop taking Madopar suddenly, as this can cause serious side effects. Always talk to your doctor first.
Use in Elderly Patients
Category A
Suitable for older adults. Consider potential interactions especially with antipsychotics and metoclopramide. (updated 6.10.2025)