Lyribastad
Lyribastad is a medicine used to treat epilepsy, nerve pain (neuropathic pain), and a type of anxiety disorder called generalized anxiety disorder in adults.
Form
kapseli, kova
Strength
300 mg
Active Ingredient
Pregabalin
Manufacturer
STADA Arzneimittel AG
How to Use
Dosage
Your doctor will determine the right dose for you, usually between 150 mg and 600 mg per day.
Method
Take the capsules whole with water. Your doctor will tell you if you should take Lyribastad two or three times a day, at about the same times each day (morning and evening for twice daily; morning, afternoon, and evening for thrice daily).
Important
The typical maximum daily dose is 600 mg.
Possible Side Effects
COMMON
- •Dizziness
- •Drowsiness
- •Headache
- •Increased appetite
- •Elevated mood
- •Confusion
- •Disorientation
- •Decreased sex drive
- •Irritability
- •Attention problems
- •Clumsiness
- •Memory impairment
- •Memory loss
- •Tremor
- •Difficulty speaking
- •Tingling
- •Numbness
- •Lethargy
- •Stupor
- •Insomnia
- •Fatigue
- •Feeling abnormal
- •Blurred vision
- •Double vision
- •Vertigo
- •Balance problems
- •Falls
- •Dry mouth
- •Constipation
- •Vomiting
- •Flatulence
- •Diarrhea
- •Nausea
- •Abdominal bloating
- •Erectile dysfunction
- •Swelling, including swelling of the limbs
- •Feeling intoxicated
- •Abnormal gait
- •Weight gain
- •Muscle cramps
- •Joint pain
- •Back pain
- •Limb pain
- •Sore throat
RARE
- •Loss of appetite
- •Weight loss
- •Low blood sugar
- •High blood sugar
- •Changes in self-perception
- •Restlessness
- •Depression
- •Agitation
- •Mood swings
- •Trouble finding words
- •Hallucinations
- •Unusual dreams
- •Panic attacks
- •Apathy
- •Aggression
- •Mental disorders
- •Difficulty thinking
- •Increased sex drive
- •Sexual problems (e.g., inability to orgasm, delayed ejaculation)
- •Changes in vision (e.g., tunnel vision, light flashes, jerky eye movements, weakened reflexes, hyperactivity, dizziness when standing, skin sensitivity, loss of taste, burning sensation, movement tremor, reduced consciousness, loss of consciousness, fainting, increased sensitivity to noise, malaise)
- •Dry eyes
- •Eye swelling
- •Eye pain
- •Reduced visual acuity
- •Watery eyes
- •Eye irritation
- •Heart rhythm disorders
- •Increased heart rate
- •Low blood pressure
- •High blood pressure
- •Changes in heart rate
- •Heart failure
- •Flushing/redness
- •Hot flashes
- •Breathing difficulties
- •Dry nose
- •Nasal congestion
- •Increased salivation
- •Heartburn
- •Numbness around the mouth
- •Sweating
- •Rash
- •Chills
- •Fever
- •Muscle twitching
- •Joint swelling
- •Muscle stiffness
- •Muscle pain
- •Neck pain
- •Chest pain
- •Difficulty or pain when urinating
- •Urinary incontinence
- •Weakness
- •Thirst
- •Tightness in the chest
- •Changes in blood and liver test results (e.g., increased blood creatinine phosphokinase, alanine aminotransferase, aspartate aminotransferase, decreased platelet count, neutropenia, increased blood creatinine, decreased blood potassium)
- •Hypersensitivity reactions
- •Face swelling
- •Itching
- •Hives
- •Runny nose
- •Nosebleed
- •Cough
- •Snoring
- •Painful periods
- •Cold hands and feet
- •Smell disorder
- •Seeing objects wobble
- •Changes in depth perception
- •Bright vision
- •Vision loss
- •Enlarged pupils
- •Squint
- •Cold sweat
- •Tightness in throat
- •Tongue swelling
- •Pancreatitis
- •Difficulty swallowing
- •Slow or reduced movements
- •Difficulty writing
- •Fluid accumulation in the abdomen
- •Fluid in the lungs
- •Seizures
- •ECG changes related to heart rhythm disorders
- •Muscle damage
- •Breast discharge
- •Abnormal breast growth
- •Breast enlargement in men
- •Missed periods
- •Kidney failure
- •Decreased urine output
- •Urinary retention
- •Decreased white blood cell count
- •Disinhibition
- •Self-harming behavior
- •Suicidal thoughts
- •Allergic reactions that may include difficulty breathing, eye inflammation, and severe skin reactions characterized by reddish, flat, target-like or ring-shaped spots with blisters in the center; skin peeling, sores in the mouth, throat, nose, genitals, and eyes. These severe rashes may be preceded by fever and flu-like symptoms (Stevens-Johnson syndrome, toxic epidermal necrolysis).
- •Yellowing of skin and eyes (jaundice)
- •Parkinsonism (symptoms resembling Parkinson's disease), such as tremor, slow movement (reduced mobility), and stiffness (muscle stiffness).
- •Liver failure
- •Hepatitis (liver inflammation)
- •Development of dependence on Lyribastad (drug dependence)
- •Breathing difficulties
- •Shallow breathing
Important Warnings
- Do not take this medicine if you are allergic to pregabalin or any other ingredients in Lyribastad.
- If you experience severe allergic reactions like swelling of the face, lips, tongue, throat, or widespread skin rash, contact your doctor immediately.
- Stop taking Lyribastad and see a doctor right away if you notice severe skin reactions like red, flat, target-like spots or blisters on your body, especially if they are accompanied by fever or flu-like symptoms.
- This medicine can cause dizziness and drowsiness, which may increase the risk of falls, especially in older people. Be careful until you know how it affects you.
- Lyribastad may cause blurred vision, vision loss, or other changes in vision. Tell your doctor right away if your vision changes.
Show 13 more warnings
- If you have diabetes and gain weight while taking Lyribastad, your diabetes medication may need to be adjusted.
- Tell your doctor before taking this medicine if you have any heart problems, as Lyribastad has been linked to heart failure in some patients.
- If you notice a decrease in urination while taking Lyribastad, tell your doctor, as kidney problems have been reported.
- If you have thoughts of harming yourself or suicide, contact your doctor immediately, as these have been reported in patients taking Lyribastad.
- If you get constipated, especially if you tend to get constipated easily, tell your doctor, as taking Lyribastad with certain other medicines can worsen stomach problems.
- Tell your doctor if you have a history of alcohol, prescription drug, or illegal drug abuse, as you may have a higher risk of becoming dependent on Lyribastad.
- If you experience seizures during or soon after stopping Lyribastad, contact your doctor immediately.
- Tell your doctor if you have a serious medical condition like liver or kidney disease, as cases of reduced brain function have been reported in some patients taking Lyribastad with other health problems.
- If you have breathing difficulties or shallow breathing, contact your doctor. This is especially important if you have nerve problems, breathing problems, kidney failure, or are over 65 years old.
- Do not stop taking Lyribastad suddenly. Talk to your doctor first, who will tell you how to gradually reduce the dose over at least one week to avoid withdrawal symptoms.
- This medicine may cause dizziness, drowsiness, and difficulty concentrating. Do not drive or operate machinery until you know how it affects you.
- Do not drink alcohol while taking Lyribastad.
- Lyribastad should only be used during pregnancy or breastfeeding if your doctor specifically advises it, as it may cause birth defects.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Sedative. Note especially central nervous system adverse effects. Reduce the dose already in mild renal impairment. Addiction may develop. (updated 14.4.2025)