Levonic
Levonic is an antibiotic that helps your body fight infections caused by bacteria, such as lung, urinary tract, prostate, and skin infections.
Form
infuusioneste, liuos
Strength
5 mg/ml
Active Ingredient
Levofloxacin hemihydrate
Manufacturer
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
How to Use
Dosage
Your doctor or nurse will decide your exact dose, which is usually 500 mg once or twice a day.
Method
This medicine is given slowly into a vein (as an infusion) by a doctor or nurse in a hospital. A 500 mg dose usually takes at least 60 minutes.
Important
The highest daily dose is usually 1000 mg.
Possible Side Effects
COMMON
- •Trouble sleeping
- •Headache, dizziness
- •Feeling sick (nausea), throwing up (vomiting), and diarrhea
- •Increased levels of certain liver enzymes in your blood
- •Reactions at the place where the medicine is given (infusion site)
- •Inflammation of a vein
RARE
- •Changes in the number of other bacteria or fungi, which can cause new infections like yeast infections
- •Changes in white blood cell counts (seen in blood tests)
- •Anxiety, confusion, nervousness, drowsiness, trembling, feeling like you're spinning (vertigo), depression, mental health problems, restlessness, unusual dreams or nightmares
- •Shortness of breath
- •Changes in taste, loss of appetite, upset stomach or indigestion, stomach pain, bloating, constipation
- •Itching and rash, severe itching or hives, unusual sweating, severe skin rashes (Stevens-Johnson syndrome, toxic epidermal necrolysis) with blisters, peeling skin, fever, or flu-like symptoms
- •Joint or muscle pain, severe joint or muscle pain, back, chest, or limb pain
- •Abnormal blood tests due to liver or kidney problems, liver inflammation, kidney problems or kidney failure due to allergic reaction
- •General weakness, severe tiredness, memory problems, severe sleep problems
- •Easy bruising or bleeding due to low platelet count
- •Low white blood cell count (neutropenia)
- •Overly active immune response (hypersensitivity), allergic reactions with rash, difficulty swallowing or breathing, swelling of lips, face, throat, or tongue
- •Low blood sugar (hypoglycemia), important for diabetics
- •Seeing or hearing things that are not there (hallucinations), paranoia
- •Tingling, burning, numbness, or weakness in hands or feet (paresthesia), burning, tingling pain or numbness (neuropathy)
- •Ringing in the ears (tinnitus) or blurred vision, temporary vision loss, decreased or lost hearing
- •Unusually fast heartbeat (tachycardia) or low blood pressure (hypotension), unusually fast heart rhythm, life-threatening irregular heart rhythm including cardiac arrest, changes in heart rhythm (prolonged QT interval on ECG)
- •Muscle weakness (important for people with myasthenia gravis), muscle breakdown (rhabdomyolysis)
- •Fever
- •Reduced red blood cells (anemia) causing pale or yellow skin, reduction of all blood cells (pancytopenia), bone marrow not producing new blood cells, reduced white blood cells (agranulocytosis)
- •Circulatory shock (anaphylactic shock-like reaction)
- •High blood sugar (hyperglycemia), important for diabetics
- •Changes in how things smell or taste, or loss of smell or taste
- •Feeling highly excited, joyful, restless, or enthusiastic (mania)
- •Difficulty moving or walking (dyskinesia, extrapyramidal disorders), sudden involuntary jerking, muscle twitching, or spasms (myoclonus)
- •Fainting (syncope)
- •Difficulty breathing or wheezing (bronchospasm), allergic lung reactions
- •Inflammation inside the mouth (stomatitis)
- •Red and swollen joints (arthritis)
- •Porphyria attacks in people who already have porphyria (a rare metabolic disorder)
- •Persistent headache with or without blurred vision (idiopathic intracranial hypertension)
- •Syndrome with reduced water excretion and low sodium levels (SIADH)
- •Low blood sugar leading to coma (hypoglycemic coma), important for diabetics
- •Enlargement or weakening of the aorta wall (aneurysms and dissections), which can rupture and be life-threatening; leaky heart valves
- •Symptoms of liver problems, such as loss of appetite, yellow skin and eyes, dark urine, itching, or tender stomach
- •Abnormal thoughts (psychotic reactions), with a risk of suicidal thoughts or attempts
- •Inflammation of the pancreas (nausea, general discomfort, stomach discomfort or pain, or vomiting)
- •Increased skin sensitivity to sunlight and UV light, darker skin areas (hyperpigmentation)
- •Inflammation of blood vessels due to an allergic reaction (vasculitis)
Important Warnings
- Do not use if you are allergic to levofloxacin, similar antibiotics (quinolones), or any other ingredients in this medicine. Tell your doctor if you've had a bad reaction to antibiotics like this before.
- Tell your doctor if you have ever had seizures or epilepsy.
- Tell your doctor if you have ever had tendon problems (like tendonitis) after taking a quinolone antibiotic.
- This medicine is not for children or growing teenagers.
- Do not use if you are pregnant, planning to get pregnant, or breastfeeding.
Show 8 more warnings
- Your skin will be more sensitive to sunlight during and for two days after treatment. Avoid direct sunlight and sunbeds. Use high SPF sunscreen and wear protective clothing.
- Stop using this medicine and get medical help right away if you develop a severe skin rash, blistering, or peeling skin, especially with fever or flu-like symptoms.
- Get emergency medical help immediately if you experience sudden, severe pain in your stomach, chest, or back. These could be signs of a serious problem with your main blood vessel (aortic aneurysm or dissection).
- Contact your doctor immediately if you suddenly have trouble breathing (especially when lying down), swelling in your ankles, feet, or stomach, or new, fast or irregular heartbeats.
- Seek immediate medical help if you experience sudden, uncontrollable jerking, twitching, or muscle spasms.
- Seek immediate medical help if you have nausea, feel generally unwell, severe or worsening stomach pain, or vomiting. These could be signs of serious inflammation of the pancreas (pancreatitis).
- Contact your doctor right away if you feel tired, have pale skin, unexplained bruises or bleeding, fever, or a sore throat. These could be signs of a serious blood disorder.
- Stop using this medicine and contact your doctor immediately if you notice signs of nerve damage (neuropathy), such as pain, burning, tingling, numbness, or weakness, especially in your hands, arms, feet, or legs.