Levomepromazine Orion
Levomepromazine Orion is a medicine used to treat severe mental health conditions like schizophrenia and psychosis, and it can also be used for severe pain relief.
Form
tabletti
Strength
25 mg
Active Ingredient
Levomepromazine maleate
Manufacturer
Orion Corporation
How to Use
Dosage
Your doctor will tell you how much medicine to take.
Method
Take the tablet with or without food. You can divide the tablet into two equal doses.
Important
Your doctor will decide your maximum daily dose.
Possible Side Effects
COMMON
- •Feeling dizzy, lightheaded, or tired, especially when you stand up at the start of treatment.
- •Shaking around the mouth (with long-term use), movements like in Parkinson's disease (shaking and stiffness), or feeling restless and unable to sit still.
- •Your heart beating faster and your blood pressure dropping.
- •Dry mouth.
- •Skin rashes, itching, or being more sensitive to sunlight.
- •Small changes in your blood test results.
RARE
- •Rhythmic, uncontrolled movements of the tongue, face, mouth, jaw, or sometimes arms and legs. Contact your doctor right away if this happens.
- •Fever, heavy sweating, stiff muscles, confusion, fast or uneven heartbeat, or big changes in blood pressure. This is very serious and needs emergency medical help immediately.
- •Severe allergic reaction with itching, rash, swelling of the face, lips, tongue, or throat, trouble breathing, and a sudden drop in blood pressure. Seek emergency medical help immediately.
- •A serious drop in white blood cells, making you more likely to get infections. Symptoms include fever, severe weakness, sore throat, or problems urinating. Contact your doctor right away.
- •Severe constipation, bloating, or stomach pain, which could mean a serious problem with your bowels (like bowel paralysis or severe inflammation). Contact your doctor right away.
- •Blurred vision for things close up, worsening of a type of glaucoma (eye pressure problem), or clouding of parts of the eye.
- •Trouble urinating.
- •Changes in your period, breasts getting bigger or feeling tender.
- •Other serious changes in your blood test results, including low platelets (cells that help blood clot), or an increase in a certain type of white blood cell (eosinophils).
- •Changes in how your body handles sugar (high blood sugar), changes in how much you want to eat, or gaining weight. Also low levels of salt (sodium) in your blood.
- •Memory problems, sudden muscle twitches or spasms, or a condition with seizures, fever, stiff muscles, and feeling confused.
- •Serious problems with your heart's rhythm or heart stopping.
- •Liver inflammation with yellowing of the skin or eyes (jaundice), or abnormal liver test results.
- •More body hair growing.
- •Changes in sexual desire and ability, delayed orgasm, problems getting or keeping an erection (impotence), or painful, long-lasting erections.
- •Blood clots in veins, possibly leading to clots in the lungs (pulmonary embolism) or deep veins (deep vein thrombosis).
Important Warnings
- Do not take this medicine if you are allergic to levomepromazine or any other ingredients in this medicine.
- Tell your doctor if you have a tumor of the adrenal gland (phaeochromocytoma).
- Tell your doctor if you have bone marrow problems.
- Tell your doctor if you have had a brain injury.
- Tell your doctor if you have ever had neuroleptic malignant syndrome, a rare and severe reaction to certain medicines.
Show 19 more warnings
- Tell your doctor if you have myasthenia gravis (a rare disease causing muscle weakness).
- Do not drink alcohol while taking this medicine, as it can increase side effects.
- If you are pregnant, breastfeeding, or planning to have a baby, talk to your doctor. You should stop breastfeeding during treatment.
- This medicine can make you sleepy and slow down your reactions. Avoid driving and using machines at the start of treatment until you know how the medicine affects you.
- Tell your doctor if you have a central nervous system disease (such as epilepsy, stroke, or dementia).
- Tell your doctor if you have any risk factors for stroke (e.g., bleeding or blood clots in the brain).
- Tell your doctor if you have heart, liver, or kidney disease.
- Tell your doctor if you have lung problems.
- Tell your doctor if you have an underactive thyroid.
- Tell your doctor if you have diabetes.
- Tell your doctor if you have glaucoma (high pressure in the eye).
- Tell your doctor if you have Parkinson's disease.
- Tell your doctor if there is a history in your family of prolonged QT interval on an ECG, which can lead to heart rhythm problems.
- Tell your doctor if there is a history in your family of blood clots, as medicines like this can cause them.
- Tell your doctor if you have a very slow heart rate.
- Tell your doctor if you have an enlarged prostate.
- Tell your doctor if you have constipation.
- Tell your doctor if you have tardive dyskinesia (uncontrolled movements).
- Tell your doctor if you are taking other antipsychotic medicines, especially those from the phenothiazine group that are not suitable for you.
Use in Elderly Patients
Category D
Avoid use in older adults. Anticholinergic. Sedative. Increases the risk of cardiovascular events, QT prolongation and orthostatic hypotension. Increases risk of falls, extrapyramidal symptoms and cognitive impairment. Reduces the effectiveness of drugs for Alzheimer’s disease. (updated 15.1.2024)