Levetiracetam Noridem
Levetiracetam Noridem is a medicine used to treat epilepsy and reduce the number of seizures.
Form
infuusiokonsentraatti, liuosta varten
Strength
100 mg/ml
Active Ingredient
Levetiracetam
Manufacturer
Noridem Enterprises Limited
How to Use
Dosage
For adults and adolescents weighing 50 kg or more, the typical dose is 1000-3000 mg daily. For children (4-11 years) and adolescents weighing less than 50 kg, the typical dose is 20-60 mg per kg of body weight daily.
Method
This medicine is given by a doctor or nurse as an infusion into a vein. It is given twice a day, once in the morning and once in the evening, around the same time each day. Each dose must be diluted in at least 100 ml of suitable liquid and given over 15 minutes.
Important
The maximum daily dose is 3000 mg.
Possible Side Effects
COMMON
- •Inflammation of the nose or throat
- •Feeling sleepy or having a headache
- •Loss of appetite
- •Depression, anger, anxiety, trouble sleeping, nervousness, or irritability
- •Seizures, balance problems, dizziness, feeling sluggish or lacking energy, or shaking
- •Spinning sensation (vertigo)
- •Cough
- •Stomach pain, diarrhea, indigestion, vomiting, or nausea
- •Rash
- •Weakness or tiredness
RARE
- •Decrease in the number of blood platelets or white blood cells
- •Weight loss or weight gain
- •Severe allergic reactions like swelling of the face, lips, tongue, or throat; difficulty breathing; or severe skin rashes
- •Suicidal thoughts or attempts, mental health issues, unusual behavior, hallucinations, anger, confusion, panic attacks, mood swings, agitation, memory loss, poor concentration, or tingling sensation (paresthesia)
- •Double vision or blurred vision
- •Increased or abnormal liver function test results
- •Hair loss, eczema, or itching
- •Muscle weakness or muscle pain, injury
- •Infection
- •Low sodium levels in the blood
- •Delirium (severe confusion and disturbed mental states)
- •Encephalopathy (a brain disease that can cause confusion, drowsiness, memory loss, abnormal behavior, or uncontrolled movements)
- •Seizures may worsen or occur more often
- •Uncontrolled twitching of muscles in the head, body, arms, and legs; hyperkinesia (overactivity)
- •Changes in heart rhythm (seen on an electrocardiogram)
- •Pancreatitis (inflammation of the pancreas), liver failure, liver inflammation, or sudden kidney failure
- •Severe skin reactions like rashes with blisters and small target-like spots (erythema multiforme), widespread blistering and peeling skin (Stevens-Johnson syndrome), or severe skin peeling over a large area of the body (toxic epidermal necrolysis)
- •Muscle breakdown (rhabdomyolysis) with high levels of creatine phosphokinase in the blood
- •Limping or difficulty walking
- •A combination of fever, muscle stiffness, unstable blood pressure, and heart rate, confusion, or low consciousness (signs of neuroleptic malignant syndrome)
- •Repeated unwanted thoughts or feelings, or a need to repeat certain actions (obsessive-compulsive disorder)
Important Warnings
- Do not use if you are allergic to levetiracetam or any other ingredients in this medicine.
- If you have kidney problems, follow your doctor's instructions as your dose may need to be changed.
- If you notice slow growth or unusual puberty development in a child, contact their doctor.
- A small number of people taking epilepsy medicine, including Levetiracetam Noridem, have had thoughts of harming themselves or suicide. If you have symptoms of depression or suicidal thoughts, contact your doctor. Also, tell your doctor if you notice significant changes in mood or behavior, such as unusual thoughts, irritability, or aggression.
- If you or your family have a history of irregular heartbeats (seen on an ECG) or if you have a condition or are receiving treatment that increases the risk of irregular heartbeats or electrolyte imbalances, tell your doctor.
Show 4 more warnings
- Your seizures may rarely get worse or happen more often, especially during the first month of treatment or after a dose increase. If this happens, contact your doctor as soon as possible.
- Do not take macrogol (a laxative) one hour before or after your Levetiracetam dose, as it may make the medicine less effective.
- This medicine can make you feel sleepy, which may affect your ability to drive or use machines. Be careful until you know how it affects you, especially at the start of treatment or when the dose is increased.
- If you are pregnant, planning to be, or breastfeeding, talk to your doctor. Levetiracetam should only be used during pregnancy if your doctor thinks it's truly necessary. Do not stop treatment without talking to your doctor. Breastfeeding is not recommended during treatment.