Letrozol Accord
Letrozol Accord is a medicine that treats breast cancer by lowering the body's estrogen levels, which slows down the growth and spread of cancer cells.
Form
tabletti, kalvopäällysteinen
Strength
2.5 mg
Active Ingredient
Letrozole
Manufacturer
Accord Healthcare B.V.
How to Use
Dosage
One tablet once a day.
Method
Swallow the tablet whole with water or another drink, with or without food, preferably at the same time each day.
Important
One tablet daily is usually the maximum dose.
Possible Side Effects
COMMON
- •Hot flashes
- •High cholesterol levels
- •Fatigue
- •Increased sweating
- •Bone or joint pain (arthralgia)
- •Rash
- •Headache
- •Dizziness
- •General feeling of unwellness
- •Stomach and bowel problems like nausea, vomiting, indigestion, constipation, diarrhea
- •Increased or decreased appetite
- •Muscle pain
- •Bone thinning or weakening (osteoporosis), possibly leading to fractures
- •Swelling in arms, hands, feet, and ankles (edema)
- •Depression
- •Weight gain
- •Hair loss
- •High blood pressure
- •Abdominal pain
- •Dry skin
- •Vaginal bleeding
- •Heart palpitations, fast heartbeat
- •Stiff joints (arthritis)
- •Chest pain
RARE
- •Weakness, paralysis, or numbness in any body part (especially arms or legs), poor coordination, nausea, speech or breathing difficulties (signs of stroke)
- •Sudden, crushing chest pain (signs of heart disease)
- •Swelling and redness along a vein, with severe tenderness and possibly pain when touched (signs of a blood clot)
- •High fever, chills, mouth sores caused by infections (due to low white blood cells)
- •Severe, persistent blurred vision
- •Tendon inflammation (tendinitis)
- •Breathing difficulties, chest pain, fainting, increased pulse, bluish discoloration of the skin, or sudden pain in an arm, leg or foot (signs of a blood clot)
- •Tendon rupture
- •Swelling, mainly in the face and throat area (signs of an allergic reaction)
- •Yellowing of skin and whites of eyes, nausea, loss of appetite, dark urine (signs of liver inflammation)
- •Rash, red skin, blisters on lips, eyes or mouth, skin peeling, fever (signs of a severe skin disease)
- •Nervous conditions such as anxiety, nervousness, irritability, drowsiness, memory problems, sleepiness, or insomnia
- •Pain or burning sensation in hands or wrists (carpal tunnel syndrome)
- •Decreased sensitivity, especially to touch
- •Eye problems such as eye irritation
- •Skin problems such as itching (hives)
- •Vaginal discharge or dryness
- •Thirst, changes in taste, dry mouth, or dry mucous membranes
- •Weight loss
- •Urinary tract infection, more frequent need to urinate
- •Cough
- •Increased enzyme levels
- •High bilirubin levels in blood (a breakdown product of red blood cells)
Important Warnings
- Do not take if you are allergic to letrozole or any other ingredients in this medicine.
- Do not take if you still have your periods or have not yet gone through menopause.
- Do not take if you are pregnant.
- Do not take if you are breastfeeding.
- Tell your doctor if you have severe kidney disease.
Show 4 more warnings
- Tell your doctor if you have severe liver disease.
- Tell your doctor if you have a history of bone weakening (osteoporosis) or fractures.
- This medicine can cause tendon inflammation or injury; if a tendon feels sore or swollen, rest the area and contact your doctor.
- Do not drive or use machines if you feel dizzy, tired, sleepy, or generally unwell until you feel normal again.