Leponex
Leponex is used to treat severe mental health conditions like schizophrenia and thought and behavior disorders in Parkinson's disease when other medications haven't worked.
Form
tabletti
Strength
200 mg
Active Ingredient
Clozapine
Manufacturer
Viatris Oy
How to Use
Dosage
Your doctor will start you on a low dose, typically 12.5 mg, and gradually increase it over time based on your condition.
Method
Swallow the tablet whole with water. It can be divided into equal doses if needed.
Important
For schizophrenia, the maximum daily dose is 900 mg. For Parkinson's-related disorders, it is 100 mg.
Possible Side Effects
COMMON
- •Drowsiness
- •Dizziness
- •Increased saliva production
- •High white blood cell count
- •Weight gain
- •Blurred vision
- •Headache
- •Tremor
- •Stiffness
- •Restlessness
- •Seizures
- •Muscle twitching
- •Abnormal movements
- •Difficulty starting movement
- •Difficulty staying still
- •Changes in ECG (heart tracing)
- •High blood pressure
- •Fainting or weakness when standing up
- •Dry mouth
- •Minor liver test changes
- •Inability to control urine
- •Difficulty urinating
- •Tiredness
- •Increased sweating
- •Fever
- •Speech problems (e.g., slurred speech)
- •Sudden fainting or loss of consciousness with muscle weakness
RARE
- •Speech problems (e.g., stuttering)
- •Weakness, dizziness or fainting when standing up (increased risk of falls)
- •Low red blood cell count (anemia)
- •Restlessness
- •Agitation
- •Confusion
- •Delirium
- •High blood sugar
- •Diabetes
- •Blood clots in the lungs (pulmonary embolism)
- •Liver inflammation (hepatitis)
- •Liver disease (yellow skin/dark urine/itching)
- •Increased creatine kinase in blood
- •Severe burning upper abdominal pain from pancreatitis with nausea/vomiting
- •Fainting and muscle weakness due to low blood pressure
- •Difficulty swallowing
- •Nausea, vomiting, or loss of appetite
- •Signs of weight gain or obesity
- •Sleep apnea (with snoring)
- •Increased blood platelets (may cause blood clots)
- •Involuntary movements of mouth/tongue/limbs
- •Obsessive thoughts/compulsive behaviors
- •Skin reactions
- •Swelling in front of the ear (enlarged salivary gland)
- •Breathing difficulties
- •Very high blood triglycerides or cholesterol
- •Sudden unexplained death
- •Persistent painful erection (priapism)
- •Spontaneous bleeding or bruising (low platelets)
- •Symptoms of poor blood sugar control (nausea/vomiting, abdominal pain, thirst, frequent urination, confusion)
- •Nausea, vomiting, tiredness, weight loss (kidney inflammation)
- •Diarrhea
- •Abdominal pain after meals
- •Muscle contractions
- •Stuffy nose
- •Bedwetting
- •Allergic reaction (swelling of face, mouth, throat, tongue, itching, or pain)
Important Warnings
- You must have regular blood tests before, during, and after treatment, as this medicine can affect your white blood cell count.
- Contact your doctor immediately if you get a fever, chills, sore throat, or other flu-like symptoms, as you may need a blood test.
- Seek immediate medical attention if you experience fast or irregular heartbeat, chest pain, or shortness of breath.
- Tell your doctor if you have severe constipation, as it needs to be treated to prevent other problems.
- This medicine can make you sleepy or dizzy, especially at the start of treatment. Do not drive or operate machinery if you feel this way.
Show 1 more warnings
- Do not drink alcohol while taking this medicine.