Lenalidomide Sandoz
Lenalidomide Sandoz is a medicine that works with your immune system and is used to treat certain blood cancers in adults.
Form
kapseli, kova
Strength
5 mg
Active Ingredient
Lenalidomide
Manufacturer
Sandoz A/S
How to Use
Dosage
Your doctor will tell you the exact dose you need to take.
Method
Swallow the capsules whole with water, with or without food, around the same time each day; do not break, open, or chew them.
Important
Your doctor will determine your daily dose as part of a 21 or 28-day treatment cycle.
Possible Side Effects
COMMON
- •Low red blood cells (anemia) causing tiredness and weakness.
- •Skin rash and itching.
- •Muscle cramps, muscle weakness, muscle pain, bone pain, joint pain, back pain, limb pain.
- •Swelling in hands, feet, or other body parts.
- •Feeling weak or tired.
- •Fever and flu-like symptoms (fever, muscle aches, headache, earache, cough, chills).
- •Numbness, tingling, or burning sensation on skin; pain in hands or feet; dizziness; tremor.
- •Reduced appetite; changes in taste.
- •Increased pain; tumor growing larger; more redness around the tumor.
- •Weight loss.
- •Constipation, diarrhea, feeling sick (nausea), throwing up (vomiting), stomach pain, heartburn.
- •Low potassium, calcium, or sodium in blood.
- •Underactive thyroid.
- •Calf pain (may be a blood clot); chest pain or shortness of breath (may be a blood clot in lungs).
- •All types of infections, including sinus, lung, and upper breathing tract infections.
- •Shortness of breath.
- •Blurry vision.
- •Cloudy eyes (cataracts).
- •Kidney problems (kidneys not working well).
- •Abnormal liver test results.
- •Changes in blood protein that can inflame arteries (vasculitis).
- •High blood sugar (diabetes).
- •Low blood sugar.
- •Headache.
- •Nosebleeds.
- •Dry skin.
- •Feeling down (depression), mood changes, trouble sleeping.
- •Cough.
- •Low blood pressure.
- •Feeling generally unwell.
- •Sore, inflamed, or dry mouth.
- •Dehydration.
- •Falls (can cause injuries).
RARE
- •Red blood cells breaking down (hemolytic anemia).
- •Some types of skin growths.
- •Bleeding from gums, stomach, or intestines.
- •High blood pressure; slow, fast, or uneven heartbeat.
- •Increased substances from red blood cell breakdown.
- •Increased protein in blood showing inflammation.
- •Darker skin; skin discoloration from bleeding under skin (bruises); skin swelling from blood.
- •High uric acid in blood.
- •Skin problems (redness, cracks, peeling, hives).
- •More sweating; night sweats.
- •Trouble swallowing; sore throat; voice changes.
- •Runny nose.
- •Peeing much more or less than usual; trouble holding pee.
- •Blood in urine.
- •Shortness of breath, especially when lying down (may be heart failure).
- •Trouble getting or keeping an erection.
- •Stroke; fainting; spinning sensation (vertigo) from inner ear problems; temporary loss of consciousness.
- •Chest pain spreading to arms, neck, jaw, back, or stomach; sweating; shortness of breath; feeling sick (nausea) or throwing up (vomiting) (may be heart attack).
- •Muscle weakness; lack of energy.
- •Neck pain; chest pain.
- •Chills.
- •Swollen joints.
- •Slow or blocked bile flow from liver.
- •Low phosphate or magnesium in blood.
- •Trouble speaking.
- •Liver damage.
- •Balance problems; trouble moving.
- •Deafness; ringing in ears (tinnitus).
- •Nerve pain; strange or unpleasant feelings especially when touched.
- •Too much iron in body.
- •Thirst.
- •Confusion.
- •Toothache.
- •Bleeding inside the head.
- •Circulation problems.
- •Worsening vision.
- •Loss of sex drive.
- •Lots of pee with bone pain and weakness (may be kidney problem called Fanconi syndrome).
- •Yellow skin, eyes, or mucous membranes (jaundice); pale poop; dark pee; itchy skin; rash; belly pain or swelling (may be liver damage).
- •Belly pain, swelling, or diarrhea (may be inflamed colon or appendix).
- •Kidney cell damage.
- •Skin color changes; sensitive to sunlight.
- •Tumor lysis syndrome (body changes from dying cancer cells causing chemical imbalances in blood, affecting kidneys, heart, and possibly leading to seizures or death).
- •High blood pressure in lung blood vessels (pulmonary hypertension).
- •Sudden or mild upper belly and/or back pain that worsens over days, possibly with nausea, vomiting, fever, and fast heartbeat (pancreatitis).
- •Wheezing, shortness of breath, or dry cough (inflammation in lung tissue).
- •Muscle breakdown (rhabdomyolysis) with muscle pain, weakness, or swelling (rare, can cause kidney problems, especially with statins).
- •Skin condition from small blood vessel inflammation (leukocytoclastic vasculitis) with joint pain and fever.
- •Stomach or intestinal wall breakdown, leading to severe infections (tell doctor about strong belly pain, fever, nausea, vomiting, bloody poop, or changed bowel habits).
- •Viral infections, including shingles (painful blistering rash) and reactivated hepatitis B (yellow skin/eyes, dark pee, right-sided belly pain, fever, nausea, or vomiting).
- •Organ transplant rejection (e.g., kidney, heart).
Important Warnings
- Do not take this medicine if you are pregnant, think you might be, or are planning to get pregnant, as it can harm an unborn baby.
- If you can become pregnant, you must use reliable birth control during treatment and for a period after.
- Do not take if you are allergic to lenalidomide or any other ingredients in this medicine.
- Tell your doctor if you have had blood clots before or if you are at high risk of getting them during treatment.
- Tell your doctor if you have signs of infection like a cough or fever.
Show 15 more warnings
- Inform your doctor if you have or have had a viral infection (like hepatitis B, shingles, or HIV), as this medicine can make it active again.
- Tell your doctor if you have kidney problems, as your dose may need to be adjusted.
- Tell your doctor if you have had a heart attack, blood clot, smoke, or have high blood pressure or cholesterol.
- Inform your doctor if you have had an allergic reaction to thalidomide (another multiple myeloma medicine), such as rash, itching, swelling, dizziness, or breathing issues.
- Tell your doctor if you have had a severe skin reaction (like DRESS or drug hypersensitivity) with widespread rash, red skin, high fever, flu-like symptoms, high liver enzymes, abnormal blood counts, and swollen lymph nodes.
- Stop taking this medicine and get urgent medical help if you have hives, rash, swelling of eyes, mouth or face, breathing difficulty, or itching, as these could be signs of a severe allergic reaction.
- Get urgent medical help if you have a severe allergic reaction that starts as a rash in one area but spreads, causing widespread skin loss (Stevens-Johnson syndrome or toxic epidermal necrolysis).
- Get urgent medical help if you have a widespread rash, high fever, elevated liver enzymes, abnormal blood counts, swollen lymph nodes, and symptoms affecting other organs (DRESS or drug hypersensitivity syndrome).
- Tell your doctor immediately if you have fever, chills, sore throat, cough, mouth sores, or other signs of infection, including blood poisoning (sepsis).
- Tell your doctor immediately if you have bleeding or bruising without injury.
- Tell your doctor immediately if you have chest or leg pain.
- Tell your doctor immediately if you have shortness of breath.
- Tell your doctor immediately if you have bone pain, muscle weakness, confusion, or tiredness, which could be due to high calcium levels in your blood.
- Tell your doctor immediately if you have blurred vision, vision loss, double vision, speech problems, arm or leg weakness, changes in walking or balance, ongoing numbness, loss of sensation, memory loss, or confusion, as these could be signs of a serious brain disease called PML.
- Tell your doctor immediately if you have shortness of breath, tiredness, dizziness, chest pain, a faster heartbeat, or swelling in your lower legs or ankles, as these could be signs of pulmonary hypertension.