Lenalidomide Ratiopharm
Lenalidomide ratiopharm is a medicine that helps your immune system work and fights cancer cells.
Form
kapseli, kova
Strength
15 mg
Active Ingredient
Lenalidomide hydrochloride hydrate
Manufacturer
Teva B.V.
How to Use
Dosage
Your doctor will decide your individual dose.
Method
Swallow capsules whole with water. Do not break, open, or chew them. You can take them with or without food, around the same time each day.
Important
Your doctor will determine your maximum daily dose as part of your treatment plan.
Possible Side Effects
COMMON
- •Lower red blood cell count, causing tiredness and weakness (anemia).
- •Rashes, itching.
- •Muscle cramps, muscle weakness, muscle pain, bone pain, joint pain, back pain, limb pain.
- •Swelling in general, including arms and legs.
- •Weakness, tiredness.
- •Fever and flu-like symptoms, including fever, muscle aches, headache, earache, cough, and chills.
- •Numbness, tingling or burning sensation on the skin, pain in hands or feet, dizziness, tremor.
- •Decreased appetite, altered taste.
- •Weight loss.
- •Constipation, diarrhea, nausea, vomiting, stomach pain, heartburn.
- •Low levels of potassium, calcium, and/or sodium in the blood.
- •Underactive thyroid gland.
- •All types of infections, including sinus, lung, and upper respiratory infections.
- •Shortness of breath.
- •Blurred vision.
- •Clouding of the eye (cataract).
- •Kidney problems, where kidneys don't work normally.
- •Abnormal liver function test results.
- •High blood sugar (diabetes).
- •Low blood sugar.
- •Headache.
- •Nosebleeds.
- •Dry skin.
- •Depression, mood changes, sleep problems.
- •Cough.
- •Low blood pressure.
- •Sore and inflamed mouth, dry mouth.
- •Dehydration.
- •Breakdown of red blood cells (hemolytic anemia).
- •Certain types of skin cancers.
- •Bleeding from gums, stomach, or intestines.
- •High blood pressure, slow, fast, or irregular heartbeat.
- •Darkening of skin, skin discoloration from bleeding under the skin (usually bruising), skin swelling from hemorrhage, bruises.
- •High uric acid levels in the blood.
- •Skin symptoms, red skin, cracked skin, flaking or peeling skin, hives.
- •Increased sweating, night sweats.
- •Difficulty swallowing, sore throat, difficulty speaking or voice changes.
- •Runny nose.
- •Passing much more or much less urine than usual, or inability to control urination.
- •Blood in urine.
- •Erection problems.
- •Stroke, fainting, vertigo (inner ear disorder causing a sensation of spinning), temporary loss of consciousness.
- •Chest pain spreading to arms, neck, jaw, back, or stomach, sweating, shortness of breath, nausea, or vomiting (signs of heart attack).
- •Muscle weakness, weakness.
- •Neck pain, chest pain.
- •Chills.
- •Joint swelling.
- •Slowed or blocked bile flow from the liver.
- •Low blood phosphate or magnesium levels.
- •Speech difficulties.
- •Liver damage.
- •Balance problems, difficulty moving.
- •Deafness, ringing in the ears (tinnitus).
- •Nerve pain, unpleasant, unusual sensations, especially when touched.
- •Too much iron in the body.
- •Thirst.
- •Confusion.
- •Toothache.
- •Falls, which can cause injuries.
RARE
- •Bleeding inside the skull.
- •Circulation problems.
- •Loss of vision.
- •Loss of sex drive (libido).
- •Passing large amounts of urine with bone pain and weakness, which may be symptoms of a kidney disorder (Fanconi syndrome).
- •Yellow skin, mucous membranes, or eyes (jaundice), pale stools, dark urine, itchy skin, rash, stomach pain or swelling – these may be signs of liver damage (liver failure).
- •Stomach pain, swelling, or diarrhea, which may be symptoms of colon inflammation (colitis or appendicitis).
- •Kidney cell damage (renal tubular necrosis).
- •Skin discoloration, sensitivity to sunlight.
- •Tumor lysis syndrome – metabolic complications that can occur during cancer treatment or sometimes without it. This happens when dying cancer cells release substances that can cause changes in blood chemistry (high potassium, phosphorus, uric acid; low calcium), leading to kidney problems, heart rhythm changes, seizures, and sometimes death.
- •High blood pressure in the blood vessels supplying the lungs (pulmonary hypertension).
Important Warnings
- Do not take this medicine if you are pregnant, think you might be pregnant, or are planning to become pregnant, as it can harm the unborn baby.
- Do not take this medicine if you are allergic to lenalidomide or any other ingredients.
- Tell your doctor if you have had blood clots before, as this medicine can increase your risk of blood clots.
- Tell your doctor if you have signs of infection like cough or fever.
- Tell your doctor if you have kidney problems, as your dose may need to be adjusted.
Show 3 more warnings
- Seek immediate medical help if you develop a widespread rash, high fever, swollen lymph nodes, or changes in blood tests, as these could be signs of a severe skin reaction (DRESS).
- Contact your doctor immediately if you experience blurred vision, speech problems, weakness on one side, or memory loss, as these could be signs of a serious brain condition (PML).
- Tell your doctor if you have shortness of breath, tiredness, dizziness, chest pain, fast heartbeat, or swollen legs/ankles, as these could be signs of a serious lung condition (pulmonary hypertension).