Lenalidomide Ratiopharm

This medicine contains lenalidomide and works by affecting your immune system and directly fighting cancer cells, helping to reduce cancer symptoms and prevent their return.

Form
kapseli, kova
Strength
10 mg
Active Ingredient
Lenalidomide hydrochloride hydrate
Manufacturer
Teva B.V.

How to Use

Dosage

Your doctor will tell you exactly how much Lenalidomide ratiopharm to take, as the dose varies based on your condition and any other medicines you are taking.

Method

Swallow the capsules whole with water. Do not break, open, or chew them. Take the medicine at about the same time each day, with or without food, as directed by your doctor.

Important

The medicine is taken in treatment cycles of 21 or 28 days, on specific days as prescribed by your doctor. Do not exceed the dose your doctor has set for each day within your cycle.

Possible Side Effects

COMMON
  • Decrease in red blood cells, which can cause anemia, leading to tiredness and weakness.
  • Rashes, itching.
  • Muscle cramps, muscle weakness, muscle pain and aches, bone pain, joint pain, back pain, limb pain.
  • Generalized swelling, including swelling of arms and legs.
  • Weakness, tiredness.
  • Fever and flu-like symptoms, including fever, muscle aches, headache, earache, cough, and chills.
  • Numbness, tingling or burning sensation in the skin, pain in hands or feet, dizziness, tremor.
  • Decreased appetite, changes in taste.
  • Increased pain, increased tumor size or increased redness around the tumor.
  • Weight loss.
  • Constipation, diarrhea, nausea, vomiting, stomach pain, heartburn.
  • Low levels of potassium, calcium, and/or sodium in the blood.
  • Underactive thyroid.
  • Leg pain (which could be a symptom of a blood clot), chest pain, or shortness of breath (which could be a symptom of blood clots in the lungs or pulmonary embolism).
  • All types of infections, including sinus infections, lung infections, and upper respiratory tract infections.
  • Shortness of breath.
  • Blurred vision.
  • Clouding of the eye (cataract).
  • Kidney problems, where kidneys cannot function normally or maintain normal function.
  • Abnormal liver function test results, increased liver enzyme levels.
  • Changes in blood proteins that can cause swelling of blood vessels (vasculitis).
  • High blood sugar (diabetes), low blood sugar.
  • Headache.
  • Nosebleeds.
  • Dry skin.
  • Depression, mood changes, sleep difficulties.
  • Cough.
  • Low blood pressure.
  • General discomfort, feeling unwell.
  • Sore and inflamed mouth, dry mouth.
  • Dehydration.
RARE
  • Destruction of red blood cells (hemolytic anemia).
  • Certain types of skin tumors.
  • Bleeding from gums, stomach or intestines.
  • High blood pressure, slow, fast or irregular heartbeat.
  • Increased levels of substances released during normal and abnormal breakdown of red blood cells.
  • Increased levels of inflammation-indicating proteins in the body.
  • Skin darkening, skin discoloration due to subcutaneous bleeding (usually bruising), skin swelling due to hemorrhage, bruises.
  • Increased uric acid levels in the blood.
  • Skin symptoms, red skin, cracked skin, flaking or peeling skin, hives.
  • Increased sweating, night sweats.
  • Difficulty swallowing, sore throat, difficulty speaking or changes in voice.
  • Runny nose.
  • Significantly more or less urine than usual, or inability to control urination.
  • Blood in urine.
  • Shortness of breath, especially when lying down (which may be a symptom of heart failure).
  • Erectile dysfunction.
  • Stroke, fainting, vertigo (inner ear disorder causing a sensation of spinning), temporary loss of consciousness.
  • Chest pain radiating to arms, neck, jaw, back, or stomach, sweating and shortness of breath, nausea or vomiting, which can be symptoms of a heart attack.
  • Muscle weakness, feeling weak.
  • Neck pain, chest pain.
  • Chills.
  • Joint swelling.
  • Slowed or blocked bile flow from the liver.
  • Low levels of phosphate or magnesium in the blood.
  • Speech difficulties.
  • Liver damage.
  • Balance disorders, difficulty moving.
  • Deafness, ringing in the ears (tinnitus).
  • Nerve pain, uncomfortable, abnormal sensations especially when touched.
  • Excessive iron in the body.
  • Thirst.
  • Confusion.
  • Toothache.
  • Falls, which can lead to injury.
  • Bleeding inside the skull.
  • Circulatory problems.
  • Loss of vision.
  • Loss of sex drive (libido).
  • Large urine output accompanied by bone pain and weakness, which may be symptoms of kidney disorder (Fanconi syndrome).
  • Yellow pigmentation of skin, mucous membranes or eyes (jaundice), pale stools, dark urine, skin itching, rash, abdominal pain or swelling – these may be symptoms of liver damage (liver failure).
  • Abdominal pain, swelling or diarrhea, which may be symptoms of large intestine inflammation (colitis or appendicitis).
  • Kidney cell damage (renal tubular necrosis).
  • Skin discoloration, sensitivity to sunlight.
  • Tumor lysis syndrome (metabolic complications that can occur during cancer treatment and sometimes without treatment).
  • Increased blood pressure within the blood vessels supplying the lungs (pulmonary hypertension).
  • Sudden or mild but worsening upper abdominal and/or back pain lasting several days, possibly with nausea, vomiting, fever, and rapid heart rate. These may be symptoms of pancreatitis.
  • Wheezing, shortness of breath, or dry cough, which may be symptoms of lung tissue inflammation.
  • Muscle tissue breakdown (muscle pain, weakness, or swelling), which can cause kidney problems (rhabdomyolysis).
  • Skin disease caused by small blood vessel inflammation, with joint pain and fever (leukocytoclastic vasculitis).
  • Breakage of the stomach or intestinal wall, which can lead to very severe infection.
  • Viral infections, including shingles (a viral infection causing painful blistering rash) and recurrence of hepatitis B infection.
  • Rejection of a solid organ transplant (such as a kidney or heart).

Important Warnings

  • Do not use if you are pregnant, think you might be pregnant, or are planning to become pregnant, as this medicine can harm the unborn baby.
  • Do not use if you are allergic to lenalidomide or any other ingredients in this medicine. If you suspect an allergy, consult your doctor.
  • Tell your doctor if you have a history of blood clots, as this medicine increases the risk of new clots in veins or arteries during treatment.
  • Inform your doctor if you have signs of infection like cough, fever, or sore throat, as the medicine can lower your white blood cell count, making you more prone to infections.
  • Stop taking this medicine and seek urgent medical help if you develop severe skin rash, swelling of the face, lips, tongue, or throat, or difficulty breathing, as these could be signs of a serious allergic reaction.
Show 1 more warnings
  • Tell your doctor if you have kidney problems, as your dose may need to be adjusted to prevent further complications.