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Lenalidomide Ratiopharm

Lenalidomide ratiopharm is a medicine that helps your body's immune system fight cancers like multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Form
kapseli, kova
Strength
5 mg
Active Ingredient
Lenalidomide hydrochloride hydrate
Manufacturer
Teva B.V.

How to Use

Dosage

Your doctor will tell you the exact dose based on your condition and disease.

Method

Swallow the capsules whole with water. Do not break, open, or chew them. You can take the medicine with or without food, at about the same time each day.

Important

Your doctor will determine the maximum daily dose, which may be adjusted based on your response and blood test results.

Possible Side Effects

COMMON
  • •Low red blood cell count (anemia), which can cause tiredness and weakness.
  • •Rash and itching.
  • •Muscle cramps, muscle pain, joint pain, and back pain.
  • •General swelling, including swelling in the arms and legs.
  • •Weakness and tiredness.
  • •Fever and flu-like symptoms, such as fever, muscle aches, headache, earache, cough, and chills.
  • •Numbness, tingling or burning sensation in the skin, pain in hands or feet, dizziness, or tremors.
  • •Reduced appetite and changes in taste.
  • •Increased pain or tumor growth.
  • •Weight loss.
  • •Constipation, diarrhea, nausea, vomiting, stomach pain, and heartburn.
  • •Low levels of potassium, calcium, or sodium in the blood.
  • •Underactive thyroid gland.
  • •Leg pain, chest pain, or shortness of breath, which could be signs of a blood clot.
  • •All types of infections, including sinus infection, lung, and upper respiratory tract infections.
  • •Shortness of breath.
  • •Blurred vision.
  • •Cataracts (clouding of the eye).
  • •Kidney problems, where the kidneys do not work properly.
  • •Abnormal or elevated liver test results.
  • •Inflammation of blood vessels (vasculitis).
  • •High blood sugar (diabetes).
  • •Low blood sugar.
  • •Headache.
  • •Nosebleed.
  • •Dry skin.
  • •Depression, mood changes, or trouble sleeping.
  • •Cough.
  • •Low blood pressure.
  • •General feeling of discomfort or unwellness.
  • •Sore and inflamed mouth, dry mouth.
  • •Dehydration.
  • •Red blood cell destruction (hemolytic anemia).
  • •Certain types of skin tumors.
  • •Bleeding from gums, stomach, or intestines.
  • •High blood pressure, slow, fast, or irregular heartbeat.
  • •Increased amounts of substances from normal and abnormal red blood cell breakdown.
  • •Increased level of an inflammation-indicating protein in the blood.
  • •Darkening of skin, bruising, or skin discoloration due to bleeding under the skin.
  • •Increased uric acid in the blood.
  • •Skin redness, cracking, peeling, or hives.
  • •Increased sweating or night sweats.
  • •Difficulty swallowing, sore throat, or voice changes.
  • •Runny nose.
  • •Changes in urine amount or inability to control urination.
  • •Blood in urine.
  • •Shortness of breath when lying down, which may be a sign of heart failure.
  • •Erection problems.
  • •Stroke, fainting, vertigo, or temporary loss of consciousness.
  • •Chest pain radiating to arms, neck, jaw, back, or stomach, sweating, shortness of breath, nausea, or vomiting, which can be signs of a heart attack.
  • •Muscle weakness or lack of energy.
  • •Neck pain or chest pain.
  • •Chills.
  • •Joint swelling.
  • •Slow or blocked bile flow from the liver.
  • •Low levels of phosphate or magnesium in the blood.
  • •Speech problems.
  • •Liver damage.
  • •Balance problems or difficulty moving.
  • •Deafness or ringing in the ears (tinnitus).
  • •Nerve pain or unpleasant, unusual sensations, especially when touched.
  • •Excess iron in the body.
  • •Thirst.
  • •Confusion.
  • •Toothache.
  • •Falls that can cause injury.
RARE
  • •Bleeding inside the skull.
  • •Circulation problems.
  • •Vision loss.
  • •Loss of sex drive.
  • •Large urine output with bone pain and weakness, which may be signs of a kidney disorder.
  • •Yellowing of skin or eyes, pale stools, dark urine, itching, rash, stomach pain, or abdominal swelling, which may be signs of liver damage.
  • •Stomach pain, swelling, or diarrhea, which may be symptoms of colon inflammation.
  • •Kidney cell damage.
  • •Skin color changes or sensitivity to sunlight.
  • •Tumor lysis syndrome (a metabolic disorder that can occur due to the breakdown of cancer cells).
  • •High blood pressure in the blood vessels of the lungs (pulmonary hypertension).
  • •Sudden or worsening upper abdominal or back pain, nausea, vomiting, fever, and rapid heart rate (may be pancreatitis).
  • •Wheezing, shortness of breath, or dry cough (may be lung inflammation).
  • •Muscle breakdown (rhabdomyolysis), which can cause muscle pain and kidney problems.
  • •Skin disease caused by small blood vessel inflammation, with joint pain and fever.
  • •Rupture of the stomach or bowel wall, which can lead to very serious infections.
  • •Viral infections, such as shingles, and reactivation of hepatitis B infection.
  • •Rejection of a solid organ transplant, such as a kidney or heart.

Important Warnings

  • Do not take if you are pregnant, think you might be pregnant, or are planning to become pregnant, as this medicine can harm an unborn baby.
  • Do not take if you are able to become pregnant and are not using reliable contraception.
  • Do not take if you are allergic to lenalidomide or any other ingredients in this medicine.
  • Tell your doctor if you have had blood clots before, as you have a higher risk of developing them during treatment.
  • Tell your doctor if you have symptoms of infection, such as a cough or fever.
Show 15 more warnings
  • Tell your doctor if you have or have had a viral infection, especially hepatitis B, as it may reactivate.
  • Tell your doctor if you have kidney problems, as your dose may need to be adjusted.
  • Tell your doctor if you have had a heart attack or blood clot, if you smoke, or if you have high blood pressure or cholesterol.
  • Tell your doctor if you have had an allergic reaction to thalidomide, another similar medicine.
  • Tell your doctor if you have had a severe skin reaction (such as widespread rash, high fever, flu-like symptoms, or swollen lymph nodes) in the past.
  • Contact your doctor immediately if you experience blurred vision, speech problems, weakness in an arm or leg, balance issues, numbness, or memory loss, as these can be signs of a serious brain condition.
  • Contact your doctor immediately if you experience shortness of breath, tiredness, dizziness, chest pain, rapid heart rate, or swelling in your legs/ankles, as these can be signs of a serious heart or lung condition.
  • If you have a severe allergic reaction, such as hives, rash, facial swelling, or difficulty breathing.
  • If you develop a severe allergic skin reaction that can spread widely and cause skin peeling (Stevens-Johnson syndrome or toxic epidermal necrolysis).
  • If you experience a widespread rash, high fever, swollen lymph nodes, or problems with your liver or other organs (DRESS syndrome).
  • Fever, chills, sore throat, cough, mouth sores, or other signs of infection, including blood poisoning.
  • Bleeding or bruising without injury.
  • Chest pain or leg pain.
  • Shortness of breath.
  • Bone pain, muscle weakness, confusion, or tiredness, which might be due to high calcium levels in the blood.

Additional Information

ATC Code: L04AX04
→ View Professional Information (PDF)→ View Patient Leaflet (PDF)