Lenalidomide Grindeks
Lenalidomide Grindeks is a medicine that helps treat certain blood cancers, such as multiple myeloma and follicular lymphoma, by affecting your immune system.
Form
kapseli, kova
Strength
25 mg
Active Ingredient
Lenalidomide ammonium chloride
Manufacturer
As Grindex
How to Use
Dosage
Your doctor will tell you exactly how much Lenalidomide Grindeks to take, as the dose varies for each person and condition.
Method
Swallow the capsules whole with water. Do not break, open, or chew them. You can take the medicine with or without food, around the same time each day.
Important
Your doctor will determine your maximum daily dose based on your specific treatment plan.
Possible Side Effects
COMMON
- •Low red blood cells (anemia), causing tiredness and weakness.
- •Rash, itching.
- •Muscle cramps, weakness, pain in muscles, bones, joints, back, arms, and legs.
- •Swelling, including in arms and legs.
- •Weakness, fatigue.
- •Fever and flu-like symptoms, muscle aches, headache, earache, cough, chills.
- •Numbness, tingling or burning sensation, pain in hands or feet, dizziness, tremor.
- •Decreased appetite, altered taste.
- •Weight loss.
- •Increased pain, tumor size, or redness around the tumor.
- •Constipation, diarrhea, nausea, vomiting, stomach pain, heartburn.
- •Low potassium, calcium, and/or sodium levels in blood.
- •Lower than normal thyroid function.
- •Leg pain (which can be a sign of a blood clot), chest pain, or shortness of breath (which can be a sign of a blood clot in the lungs).
- •All types of infections, including in the sinuses, lungs, and upper airways.
- •Shortness of breath.
- •Blurred vision.
- •Clouding of the eye (cataract).
- •Kidney problems, including kidneys not working properly.
- •Abnormal or high liver test results.
- •Changes in blood protein that can cause artery swelling (vasculitis).
- •High or low blood sugar levels (diabetes).
- •Headache.
- •Nosebleed.
- •Dry skin.
- •Depression, mood changes, difficulty sleeping.
- •Cough.
- •Low blood pressure.
- •General feeling of discomfort or illness.
- •Sore, inflamed mouth, dry mouth.
- •Dehydration.
- •Breakdown of red blood cells (hemolytic anemia).
- •Certain types of skin tumors.
- •Bleeding from gums, stomach, or intestines.
- •High blood pressure, slow, fast, or irregular heartbeat.
- •Darkening of skin, bruising, skin discoloration due to bleeding under the skin.
- •Increased uric acid levels in blood.
- •Skin symptoms like redness, cracking, peeling skin, hives.
- •Increased sweating, night sweats.
- •Difficulty swallowing, sore throat, changes in voice.
- •Runny nose.
- •Very high or low urine output, or inability to control urination.
- •Blood in urine.
- •Shortness of breath, especially when lying down (which can be a sign of heart failure).
- •Erectile dysfunction.
- •Stroke, fainting, spinning sensation (vertigo), temporary loss of consciousness.
- •Chest pain that spreads to arms, neck, jaw, back, or stomach, sweating, shortness of breath, nausea, or vomiting, which can be signs of a heart attack.
- •Muscle weakness, lack of energy.
- •Neck pain, chest pain.
- •Chills.
- •Joint swelling.
- •Slow or blocked bile flow from the liver.
- •Low phosphate or magnesium in blood.
- •Difficulty speaking.
- •Liver damage.
- •Balance problems, difficulty moving.
- •Deafness, ringing in ears (tinnitus).
- •Nerve pain, uncomfortable or unusual sensations, especially when touched.
- •Too much iron in the body.
- •Thirst.
- •Confusion.
- •Toothache.
- •Falls that may lead to injury.
RARE
- •Bleeding inside the skull.
- •Circulation problems.
- •Loss of vision.
- •Loss of sex drive (libido).
- •Large amount of urine with bone pain and weakness, possibly signs of a kidney disorder (Fanconi syndrome).
- •Yellow skin, mucous membranes, or eyes (jaundice), pale stools, dark urine, itchy skin, rash, stomach pain, or swollen abdomen – these can be signs of liver damage.
- •Stomach pain, swelling, or diarrhea, which can be signs of large intestine inflammation (colitis or appendicitis).
- •Kidney cell damage (renal tubular necrosis).
- •Skin color changes, sensitivity to sunlight.
- •Tumor lysis syndrome – complications from fast breakdown of cancer cells, leading to changes in blood chemistry, kidney problems, heart rhythm changes, seizures, and potentially death.
- •High blood pressure in the arteries of the lungs (pulmonary hypertension).
- •Sudden or mild but worsening upper abdominal and/or back pain lasting for several days, possibly with nausea, vomiting, fever, and fast heart rate. These could be signs of pancreatitis.
- •Wheezing, shortness of breath, or dry cough, which could be signs of lung tissue inflammation.
- •Muscle breakdown (rhabdomyolysis), causing muscle pain, weakness, or swelling, potentially leading to kidney problems.
- •Skin condition caused by inflammation of small blood vessels (leukocytoclastic vasculitis), with joint pain and fever.
- •Breakage of the stomach or intestinal wall, which can lead to severe infection. Tell your doctor if you have severe stomach pain, fever, nausea, vomiting, bloody stools, or changes in bowel habits.
- •Viral infections, including shingles (painful blistering rash) and recurrence of Hepatitis B infection (yellow skin/eyes, dark urine, right-sided abdominal pain, fever, nausea, vomiting).
- •Rejection of a solid organ transplant (e.g., kidney, heart).
Important Warnings
- Do not take if you are pregnant, think you might be pregnant, or are planning to get pregnant, as this medicine can harm the unborn baby.
- If you can become pregnant, you must use effective birth control methods during and after treatment.
- Do not take if you are allergic to lenalidomide or any other ingredients in this medicine.
- This medicine increases the risk of blood clots. Tell your doctor if you have had blood clots before.
- Tell your doctor if you have signs of infection like cough or fever.
Show 7 more warnings
- If you have or have had a viral infection (like Hepatitis B, chickenpox, or HIV), this medicine might reactivate it. Your doctor will check for Hepatitis B.
- If you have kidney problems, your doctor might need to adjust your dose.
- Tell your doctor if you have had a heart attack, blood clots, smoke, or have high blood pressure or high cholesterol.
- Inform your doctor if you had an allergic reaction (like rash, itching, swelling, dizziness, or breathing difficulties) to thalidomide in the past.
- If you've had a severe skin reaction with symptoms like widespread rash, red skin, fever, flu-like symptoms, or swollen lymph nodes, tell your doctor.
- Seek immediate medical help if you experience vision changes, speech problems, weakness in arms/legs, balance issues, numbness, memory loss, or confusion, as these could be signs of a serious brain condition (PML).
- Tell your doctor right away if you have shortness of breath, tiredness, dizziness, chest pain, fast heartbeat, or swelling in your legs/ankles, as these can be signs of a serious lung condition.