Lenalidomide Grindeks
Lenalidomide Grindeks is a medicine used to treat certain blood cancers called multiple myeloma and follicular lymphoma in adults by affecting the immune system.
Form
kapseli, kova
Strength
15 mg
Active Ingredient
Lenalidomide ammonium chloride
Manufacturer
As Grindex
How to Use
Dosage
Your doctor will tell you the exact dose you need to take based on your treatment cycle.
Method
Swallow the capsules whole with water. Do not break, open, or chew them. You can take the capsules with or without food. Take the medicine on your scheduled days at roughly the same time.
Important
Your doctor will determine your maximum daily dose as part of your overall treatment plan.
Possible Side Effects
COMMON
- •Low red blood cell count (anemia), which can cause tiredness and weakness.
- •Rash and itching.
- •Muscle cramps, muscle weakness, muscle pain, joint pain, back pain, and pain in the arms and legs.
- •General swelling, including swelling in the arms and legs.
- •Weakness and tiredness.
- •Fever and flu-like symptoms, such as fever, muscle aches, headache, ear pain, cough, and chills.
- •Numbness, tingling or burning sensation on the skin, pain in the hands or feet, dizziness, and tremors.
- •Reduced appetite and changes in taste.
- •Increased pain, growth in tumor size, or redness around the tumor.
- •Weight loss.
- •Constipation, diarrhea, nausea, vomiting, stomach pain, and heartburn.
- •Low levels of potassium, calcium, and/or sodium in the blood.
- •Underactive thyroid.
- •Leg pain (may be a symptom of a blood clot), chest pain or shortness of breath (may be a symptom of a blood clot in the lungs).
- •All types of infections, including sinus infection, lung, and upper respiratory tract infections.
- •Shortness of breath.
- •Blurred or weakened vision.
- •Cataract (clouding of the eye).
- •Kidney problems, which can lead to reduced kidney function.
- •Abnormal liver function tests or elevated liver enzyme levels.
- •Changes in blood proteins that can cause blood vessel inflammation (vasculitis).
- •High or low blood sugar levels (diabetes).
- •Headache.
- •Nosebleed.
- •Dry skin.
- •Depression, mood changes, sleep disturbances.
- •Cough.
- •Low blood pressure.
- •General feeling of being unwell.
- •Sore and inflamed mouth, dry mouth.
- •Dehydration.
- •Bleeding from gums, stomach, or intestines.
- •High blood pressure, slow, fast, or irregular heartbeat.
- •Increased substance resulting from normal and abnormal breakdown of red blood cells.
- •Increased protein indicating inflammation in the body.
- •Skin darkening, bruising, skin swelling due to bruises.
- •Increased uric acid in blood.
- •Rash: red, cracking, peeling skin, or hives.
- •Increased sweating, night sweats.
- •Difficulty swallowing, sore throat, changes in voice quality or voice.
- •Runny nose.
- •Changes in urine volume (too much or too little), blood in urine, or inability to control urine.
- •Erectile dysfunction.
- •Stroke, fainting, vertigo (inner ear disorder), temporary loss of consciousness.
- •Chest pain radiating to arms, neck, jaw, back or stomach, sweating, shortness of breath, nausea or vomiting (symptoms of a heart attack).
- •Muscle weakness or lack of strength.
- •Neck or chest pain.
- •Chills.
- •Joint swelling.
- •Slowed or blocked bile flow from the liver.
- •Low blood phosphate or magnesium levels.
- •Speech difficulties.
- •Liver damage.
- •Balance problems, difficulty moving.
- •Deafness, ringing in the ears (tinnitus).
- •Nerve pain, unpleasant or abnormal sensations, especially when touched.
- •Excess iron in the body.
- •Thirst.
- •Confusion.
- •Toothache.
- •Falls that can lead to injury.
RARE
- •Bleeding inside the skull.
- •Circulatory problems.
- •Loss of vision.
- •Loss of libido (decreased sex drive).
- •Large amounts of urine with bone pain and weakness, which can be symptoms of a kidney disease (Fanconi syndrome).
- •Yellowing of the skin, mucous membranes, or eyes (jaundice), pale stools, dark urine, itchy skin, rash, abdominal pain, or abdominal swelling – these may be symptoms of liver damage (liver failure).
- •Abdominal pain, swelling, or diarrhea, which can be symptoms of colon or appendicitis inflammation.
- •Damage to kidney cells (renal tubular necrosis).
- •Skin color changes, sensitivity to sunlight.
- •Tumor lysis syndrome – metabolic complications that can occur during cancer treatment or even without treatment.
- •Pulmonary hypertension – high blood pressure in the blood vessels supplying the lungs.
- •Sudden or worsening upper abdominal and/or back pain, possibly with nausea, vomiting, fever, and a fast heartbeat. These can be symptoms of pancreatitis.
- •Wheezing, shortness of breath, or dry cough, which can be symptoms of lung tissue inflammation.
- •Muscle tissue breakdown (muscle pain, weakness, or swelling), which can cause kidney problems (rhabdomyolysis).
- •Skin disease caused by small blood vessel inflammation, with joint pain and fever (leukocytoclastic vasculitis).
- •Stomach or intestinal wall rupture, which can lead to very severe infection.
- •Viral infections, such as shingles and recurrence of hepatitis B infection.
- •Rejection of a solid organ transplant (such as a kidney, heart).
Important Warnings
- Do not take if you are pregnant, think you might be pregnant, or plan to become pregnant, as this medicine can seriously harm the unborn baby.
- If you can become pregnant, you must use reliable birth control during and for at least 4 weeks after taking this medicine.
- Men should use a condom during treatment and for 7 days after if their partner can become pregnant.
- Do not take if you are allergic to lenalidomide or any other ingredients in this medicine.
- Tell your doctor if you have had blood clots before, as you have a higher risk of getting them during treatment.
Show 8 more warnings
- Tell your doctor if you have symptoms of an infection, such as a cough or fever.
- Tell your doctor if you have or have had a viral infection, such as hepatitis B, chickenpox, or HIV.
- Tell your doctor if you have kidney problems, as your dose may need to be changed.
- Tell your doctor if you have had a heart attack, blood clots, smoke, or have high blood pressure or high cholesterol.
- Tell your doctor if you have had an allergic reaction to thalidomide (e.g., rash, itching, swelling, dizziness, breathing difficulties).
- Tell your doctor if you have had severe skin reactions like widespread rash, high fever, flu-like symptoms, or enlarged lymph nodes.
- Contact your doctor immediately if you develop blurred vision, speech difficulties, weakness in your limbs, balance problems, numbness, memory loss, or confusion, as these could be signs of a serious brain disease (PML).
- Contact your doctor immediately if you develop shortness of breath, fatigue, dizziness, chest pain, a fast heartbeat, or swelling in your legs or ankles, as these could be signs of pulmonary hypertension.