Lenalidomid Avansor
Lenalidomid Avansor is a medicine that works with your immune system and directly targets cancer cells to treat certain blood cancers.
Form
kapseli, kova
Strength
15 mg
Active Ingredient
Lenalidomide
Manufacturer
Avansor Pharma Oy
How to Use
Dosage
Your doctor will tell you exactly how much to take, as the dose varies depending on your condition and other medications.
Method
Swallow the capsules whole with water. Do not break, open, or chew them. You can take them with or without food, at the same time each day as directed by your doctor.
Important
The maximum daily dose will be determined by your doctor as part of your treatment cycle, which can be 21 or 28 days long.
Possible Side Effects
COMMON
- •Anemia (low red blood cells), fatigue, weakness
- •Rashes, itching
- •Muscle cramps, muscle pain, bone pain, joint pain, back pain, limb pain, muscle weakness
- •Swelling in arms and legs
- •General weakness, fatigue
- •Fever, flu-like symptoms (e.g., muscle aches, headache, cough, chills)
- •Numbness, tingling, burning sensation on skin, pain in hands or feet, dizziness, tremor, decreased appetite, changes in taste
- •Increased pain, larger tumor size, or more redness around the tumor
- •Weight loss
- •Constipation, diarrhea, nausea, vomiting, stomach pain, heartburn
- •Low blood levels of potassium, calcium, or sodium
- •Underactive thyroid
- •Leg pain (may be a blood clot), chest pain, shortness of breath (may be a lung clot)
- •All types of infections, including sinus, lung, and upper respiratory infections
- •Shortness of breath
- •Blurred or weakened vision
- •Clouding of the eye (cataract)
- •Kidney problems
- •Abnormal liver function test results
- •Increased liver function test results
- •Changes in blood protein that can cause blood vessel inflammation (vasculitis)
- •Increased blood sugar (diabetes)
- •Decreased blood sugar
- •Headache
- •Nosebleeds
- •Dry skin
- •Depression, mood changes, trouble sleeping
- •Cough
- •Low blood pressure
- •General feeling of being unwell
- •Sore, inflamed mouth, dry mouth
- •Dehydration
- •Red blood cell breakdown (hemolytic anemia)
- •Certain types of skin tumors
- •Bleeding from gums, stomach, or intestines
- •High blood pressure, slow, fast, or irregular heartbeat
- •Increased substance from red blood cell breakdown
- •Increased inflammation markers in blood
- •Darkened skin, bruising, skin discoloration due to bleeding under the skin
- •Increased uric acid in blood
- •Skin symptoms like redness, cracking, flaking, or hives
- •Increased sweating, night sweats
- •Difficulty swallowing, sore throat, voice changes
- •Runny nose
- •Increased or decreased urine output, loss of bladder control
- •Blood in urine
- •Shortness of breath, especially when lying down (may be a sign of heart failure)
- •Erectile dysfunction
- •Stroke, fainting, vertigo, temporary loss of consciousness
- •Chest pain radiating to arms, neck, jaw, back, or stomach, sweating, shortness of breath, nausea, or vomiting (may be signs of a heart attack)
- •Muscle weakness, lack of energy
- •Neck pain, chest pain
- •Chills
- •Joint swelling
- •Slowed or blocked bile flow from the liver
- •Low blood phosphate or magnesium
- •Speech difficulties
- •Liver damage
- •Balance problems, difficulty moving
- •Deafness, ringing in ears (tinnitus)
- •Nerve pain, unusual or unpleasant sensations, especially when touched
- •Excess iron in the body
- •Thirst
- •Confusion
- •Toothache
- •Falls that may cause injury
RARE
- •Bleeding inside the skull
- •Circulatory problems
- •Loss of vision
- •Loss of sex drive
- •High urine output with bone pain and weakness (may be signs of a kidney disorder)
- •Yellow skin or eyes (jaundice), pale stools, dark urine, itchy skin, rash, stomach pain or swelling (may be signs of liver damage)
- •Stomach pain, swelling or diarrhea (may be signs of colon inflammation)
- •Kidney cell damage (renal tubular necrosis)
- •Skin color changes, sensitivity to sunlight
- •Tumor lysis syndrome (complications from cancer cells breaking down)
- •High blood pressure in the lung arteries (pulmonary hypertension)
- •Sudden or worsening stomach or back pain with nausea, vomiting, fever, and fast heart rate (may be pancreatitis)
- •Wheezing, shortness of breath, or dry cough (may be lung inflammation)
- •Muscle breakdown (muscle pain, weakness, swelling) that can lead to kidney problems (rhabdomyolysis)
- •Skin disease from small blood vessel inflammation, with joint pain and fever (leukocytoclastic vasculitis)
- •Rupture of stomach or intestinal wall, leading to severe infection
- •Viral infections like shingles or reactivated hepatitis B (can cause yellow skin/eyes, dark urine, abdominal pain, fever, nausea/vomiting)
- •Organ transplant rejection (e.g., kidney, heart)
Important Warnings
- Do not take this medicine if you are pregnant, suspect you are pregnant, or plan to become pregnant, as it can severely harm the unborn baby.
- If you can become pregnant, you must use effective birth control before, during, and after treatment.
- Do not take this medicine if you are allergic to lenalidomide or any other ingredient in it.
- Tell your doctor if you have had blood clots, an infection, kidney problems, a heart attack, or high blood pressure or cholesterol before, as this medicine may increase risks.
- Inform your doctor if you have or have had a viral infection, such as hepatitis B, chickenpox, or HIV, as this medicine can reactivate viruses.
Show 3 more warnings
- Tell your doctor if you have had a severe allergic skin reaction to thalidomide or any other medicine, with widespread rash, fever, or swollen lymph nodes.
- Seek immediate medical attention if you experience blurred vision, speech problems, weakness, memory loss, or confusion, as these could be signs of a serious brain condition (PML).
- Seek immediate medical attention if you experience shortness of breath, fatigue, chest pain, fast heartbeat, or swelling in your legs or ankles, as these could be signs of pulmonary hypertension.