Lamotrigin ratiopharm

Lamotrigin ratiopharm is a medicine used to treat two conditions: epilepsy, by blocking seizure signals in the brain, and bipolar disorder, by helping to stabilize mood.

Form
dispergoituva tabletti
Strength
200 mg
Active Ingredient
Lamotrigine
Manufacturer
ratiopharm GmbH

How to Use

Dosage

For adults and children over 13 years old: typically 100-400 mg daily. For children aged 2-12 years: 1-15 mg per kg of body weight daily, up to a maximum of 200 mg.

Method

Take once or twice a day as your doctor instructs, with or without food. Swallow the tablet whole with a small amount of water or dissolve it in water to drink. Always take the full dose; never take only part of a tablet.

Important

Never take more than your doctor prescribes. For adults and children over 13 years old, the maximum is 400 mg per day. For children aged 2-12 years, the maximum is 200 mg per day.

Possible Side Effects

COMMON
  • Headache
  • Rash
  • Irritability or annoyance
  • Tiredness or sleepiness
  • Dizziness
  • Tremor or shaking
  • Difficulty sleeping (insomnia)
  • Restlessness
  • Diarrhea
  • Dry mouth
  • Nausea or vomiting
  • Feeling tired
  • Back, joint, or other pain
RARE
  • Clumsiness or poor coordination
  • Double or blurred vision
  • Unusual hair loss
  • Rash or sunburn after sun exposure
  • Severe skin reactions, such as widespread blistering or peeling skin (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome)
  • A syndrome with fever, nausea, vomiting, headache, stiff neck, and sensitivity to bright light (meningitis symptoms)
  • Rapid, uncontrolled eye movements
  • Itchy, watery eyes and crusty eyelids (conjunctivitis)
  • High fever
  • Swelling of the face or swollen glands in the neck, armpits, or groin
  • Changes in liver function or liver failure
  • Severe blood clotting disorder that can cause unexpected bleeding or bruising
  • Immune system reaction (hemophagocytic lymphohistiocytosis, HLH)
  • Changes in blood tests (e.g., decrease in red blood cells, white blood cells, or platelets)
  • Hallucinations (seeing or hearing things that aren't real)
  • Confusion
  • Feeling unsteady when moving
  • Uncontrolled repetitive body movements, sounds, or words (tics), uncontrolled muscle spasms or twitches (choreoathetosis)
  • More frequent or worse seizures for those who already have epilepsy
  • Worsening of Parkinson's disease symptoms
  • Lupus-like reaction (symptoms include back or joint pain, fever, and general malaise)
  • Bone changes, such as weakened bones and fractures
  • Kidney inflammation or inflammation of both the kidney and eye
  • Nightmares
  • Weakened immune system
  • Red lumps or spots on the skin (pseudolymphoma)

Important Warnings

  • Do not take if you are allergic to lamotrigine or any other ingredient in this medicine.
  • Seek immediate medical attention if you experience a severe skin rash, fever, or any new or worsening skin reactions, as these could be life-threatening.
  • Tell your doctor if you have kidney problems or heart conditions like Brugada syndrome, as your dose may need to be adjusted.
  • Inform your doctor if you have had meningitis after taking lamotrigine.
  • Contact your doctor immediately if you have thoughts of harming yourself or notice significant mood changes.
Show 5 more warnings
  • Seek immediate medical help if your seizures become more frequent or severe.
  • This medicine is not for treating bipolar disorder in people under 18 years old.
  • Do not stop taking this medicine suddenly without talking to your doctor, especially if you have epilepsy, as it can worsen your condition.
  • Do not drive or use machines if you feel dizzy or have blurred vision.
  • Tell your doctor about all other medicines you are taking, including herbal remedies, as they can interact with Lamotrigin ratiopharm.

Use in Elderly Patients

Category C

Suitable for older adults, with specific precautions. Numerous potential adverse effects.. Consider common and sometimes serious adverse skin reactions. Reduce the dose in severe renal impairment. (updated 6.10.2025)