Lamotrigin ratiopharm
Lamotrigine ratiopharm is a medicine used to treat epilepsy and bipolar disorder, which helps control seizures and mood swings.
Form
dispergoituva tabletti
Strength
100 mg
Active Ingredient
Lamotrigine
Manufacturer
ratiopharm GmbH
How to Use
Dosage
For adults and children aged 13 and older, the usual dose is between 100 mg and 400 mg daily. For children aged 2-12, the dose depends on their weight, typically 1 mg to 15 mg per kilogram of body weight per day, up to a maximum of 200 mg daily.
Method
Take your dose once or twice a day, exactly as prescribed by your doctor. You can take it with or without food. You can swallow the tablets whole with a little water or dissolve them in water to make a liquid medicine. Always take the full dose your doctor prescribed.
Important
The maximum daily dose for adults is 400 mg, and for children (2-12 years old) up to 200 mg.
Possible Side Effects
COMMON
- •Headache
- •Rash
- •Irritability or aggression
- •Tiredness or sleepiness
- •Dizziness
- •Shaking or tremor
- •Difficulty sleeping (insomnia)
- •Agitation
- •Diarrhea
- •Dry mouth
- •Nausea or vomiting
- •Feeling tired
- •Back, joint, or other pain
RARE
- •Clumsiness or lack of coordination (ataxia)
- •Double vision or blurred vision
- •Unusual hair loss or thinning (alopecia)
- •Rash or sunburn after exposure to sun or artificial light (photosensitivity)
- •Life-threatening skin reaction (Stevens-Johnson syndrome), with widespread blistering and peeling skin, especially around the mouth, nose, eyes, and genitals.
- •Symptoms like fever, nausea, vomiting, headache, stiff neck, and extreme sensitivity to bright light, which could be due to inflammation of the membranes protecting the brain and spinal cord (meningitis).
- •Rapid, uncontrolled eye movements (nystagmus)
- •Itchy, watery eyes and crusty eyelids (conjunctivitis)
- •Very serious life-threatening skin reaction (toxic epidermal necrolysis), with extensive skin peeling over large areas of the body.
- •DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms), a severe allergic reaction that can affect multiple body organs.
- •High fever
- •Swelling of the face or swollen glands in the neck, armpits, or groin (lymphadenopathy)
- •Changes in liver function as seen in blood tests, or liver failure.
- •Severe blood clotting disorder (DIC) that can cause unexpected bleeding or bruising.
- •Hemophagocytic lymphohistiocytosis (HLH), a rare but very serious immune system reaction.
- •Blood test changes, including low red or white blood cells, low platelets, or bone marrow disorder (aplastic anemia).
- •Hallucinations (seeing or hearing things that are not real).
- •Confusion
- •Feeling unsteady or wobbly when moving.
- •Uncontrolled repetitive body movements and/or sounds or words (tics), uncontrolled muscle spasms affecting eyes, head, or torso (choreoathetosis), or other unusual body movements like twitching, shaking, or stiffness.
- •More frequent seizures in people who already have epilepsy.
- •Worsening symptoms in people who already have Parkinson’s disease.
- •Lupus-like reaction (symptoms may include back or joint pain, sometimes with fever and/or a general feeling of being unwell).
- •Bone changes like weakening (osteopenia, osteoporosis) and fractures.
- •Kidney inflammation (tubulointerstitial nephritis), or inflammation in both the kidney and eye (tubulointerstitial nephritis and uveitis).
- •Nightmares
- •Weakened immune system due to lower levels of immunoglobulins, which are blood proteins that help fight infections.
- •Red lumps or spots on the skin (pseudolymphoma).
Important Warnings
- Do not take this medicine if you are allergic to lamotrigine or any other ingredients in the medicine.
- Contact your doctor immediately if you develop a rash, fever, or any neurological symptoms like shaking, confusion, or problems with brain function.
- If you have kidney problems, have had a rash from other medicines, get a rash or sunburn easily, have had meningitis, or have heart problems (like Brugada syndrome), tell your doctor before taking this medicine.
- Some people taking this medicine for epilepsy may have their seizures worsen or become more frequent; if this happens, contact your doctor right away.
- A small number of people taking epilepsy medicines like this one have had thoughts of harming themselves or suicide; if you ever have these thoughts, contact your doctor immediately.
Show 3 more warnings
- Do not stop taking this medicine without talking to your doctor, especially if you have epilepsy, as stopping suddenly can worsen your condition.
- If you are pregnant, planning to become pregnant, or breastfeeding, ask your doctor or pharmacist for advice before using this medicine.
- This medicine can make you feel dizzy or see double. Do not drive or operate machinery until you know how it affects you.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. Numerous potential adverse effects.. Consider common and sometimes serious adverse skin reactions. Reduce the dose in severe renal impairment. (updated 6.10.2025)