Kliogest

Kliogest is a hormone replacement medicine used daily by postmenopausal women to relieve menopausal symptoms like hot flashes and to prevent bone thinning (osteoporosis).

Form
tabletti, kalvopäällysteinen
Active Ingredient
Estradiol hemihydrate
Manufacturer
Novo Nordisk A/S

How to Use

Dosage

Take one tablet once a day.

Method

Swallow one tablet whole with a glass of water, taking it every day without interruption.

Important

Do not take more than one tablet per day.

Possible Side Effects

COMMON
  • Breast pain or tenderness
  • Vaginal bleeding
  • Headache
  • Weight gain from fluid retention
  • Vaginal inflammation or yeast infection
  • New or worsening migraine
  • Depression or worsening mood
  • Nausea
  • Abdominal pain, bloating, or discomfort
  • Breast enlargement or swelling
  • Back pain or leg cramps
  • Worsening or recurrence of uterine fibroids
  • Swelling in hands or feet
  • Weight gain
RARE
  • Blood clots in leg veins or lungs
  • Cancer of the uterine lining or its overgrowth
  • Increased blood pressure or worsening high blood pressure
  • Gallbladder problems or gallstones
  • Sudden swelling of face, tongue, or throat (angioedema)
  • Insomnia, dizziness, or restlessness
  • Changes in sex drive
  • Vision changes
  • Weight loss or vomiting
  • Skin issues like acne, hair loss, abnormal hair growth, itching, or hives
  • Heart attack and stroke

Important Warnings

  • Do not take Kliogest if you have or have had breast cancer, uterine cancer, or blood clots.
  • Do not take Kliogest if you have unexplained vaginal bleeding or severe liver disease.
  • Stop taking Kliogest and call your doctor right away if your skin or eyes turn yellow, you have sudden swelling of your face/throat, signs of a blood clot (like leg pain or chest pain), or a sudden bad headache.
  • If you become pregnant, stop taking Kliogest and talk to your doctor.
  • Do not take Kliogest if you are allergic to any of its ingredients.

Use in Elderly Patients

Category D

Systemic use: Avoid use in older adults. In systemic use, consider potential adverse effects, such as risk of cardiovascular diseases and venous thromboembolism. Consider potential interactions. (updated 21.10.2024)