Indivina
Indivina is a hormone replacement therapy that helps relieve menopause symptoms and prevent bone loss in women whose periods stopped at least three years ago.
Form
tabletti
Strength
1 mg / 5 mg
Active Ingredient
Estradiol valerate
Manufacturer
Orion Corporation
How to Use
Dosage
Take one Indivina tablet once a day.
Method
Swallow the tablet whole with liquid, preferably at about the same time each day.
Important
Your doctor will prescribe the lowest possible dose for the shortest possible time; do not exceed the dose prescribed by your doctor.
Possible Side Effects
COMMON
- •Weight gain or loss
- •Swelling due to fluid retention
- •Feeling down (depression)
- •Nervousness
- •Lack of energy
- •Headache
- •Dizziness
- •Hot flashes
- •Increased sweating
- •Nausea
- •Vomiting
- •Stomach cramps
- •Gas
- •Breast pain or tenderness
- •Vaginal discharge
- •Irregular vaginal bleeding or spotting
- •Disorders of external genitalia or vagina
- •Menstrual disorders
RARE
- •Benign breast tumor
- •Benign uterine lining growth
- •Allergic reaction
- •Increased appetite
- •High blood cholesterol levels
- •Anxiety
- •Insomnia
- •Apathy
- •Mood swings
- •Difficulty concentrating
- •Changes in mood or sex drive
- •Strong feeling of happiness (euphoria)
- •Agitation
- •Migraine
- •Sensory disturbances (tingling/numbness)
- •Shaking
- •Vision disturbances
- •Dry eyes
- •Feeling heart palpitations
- •Increased blood pressure
- •Superficial vein inflammation
- •Purple bruise-like spots
- •Shortness of breath
- •Runny or blocked nose
- •Constipation
- •Upper abdominal discomfort
- •Diarrhea
- •Rectal disorders
- •Acne
- •Hair loss
- •Dry skin
- •Nail disorders
- •Skin lumps
- •Excessive hair growth (hirsutism)
- •Erythema nodosum (painful red lumps on the skin)
- •Hives
- •Joint disorders
- •Muscle cramps
- •Frequent urination or increased urge to urinate
- •Urinary incontinence
- •Bladder infection
- •Changes in urine color
- •Blood in urine
- •Breast enlargement
- •Breast tenderness
- •Uterine lining thickening
- •Uterine disorders
- •Fatigue
- •Abnormal laboratory test results
- •Weakness
- •Fever
- •Flu-like symptoms
- •General feeling of illness
Important Warnings
- If you have or have had breast cancer or other estrogen-dependent cancer, or if there is a suspicion of such.
- If you have unexplained vaginal bleeding.
- If you have untreated endometrial hyperplasia (excessive thickening of the womb lining).
- If you have or have had a blood clot in a vein (e.g., in your leg or lungs).
- If you have a disorder that increases your risk of blood clots (e.g., deficiency of protein C, S, or antithrombin).
Show 10 more warnings
- If you have or have recently had a disease caused by arterial blood clots, such as a heart attack, stroke, or angina.
- If you have or have had liver disease and your liver function tests have not returned to normal.
- If you have porphyria (a rare, inherited blood disorder).
- If you are allergic to estradiol valerate, medroxyprogesterone acetate, or any other ingredient in this medicine.
- Your skin or the whites of your eyes turn yellow (jaundice), as this may indicate a liver problem.
- You experience symptoms of angioedema (e.g., swelling of the face, tongue, and/or throat, difficulty swallowing, or hives with breathing difficulties).
- Your blood pressure rises significantly (this can cause headache, tiredness, dizziness).
- You get a migraine-type headache for the first first time.
- You become pregnant.
- You notice signs of a blood clot, such as painful swelling and redness in your legs, sudden chest pain, or difficulty breathing.
Use in Elderly Patients
Category D
Avoid use in older adults. Consider potential interactions. (updated 21.10.2024)