Imatinib Orion
Imatinib Orion is a medicine that helps stop the growth of abnormal cancer cells in certain serious diseases.
Form
kapseli, kova
Strength
100 mg
Active Ingredient
Imatinib mesylate
Manufacturer
Cipla Europe NV
How to Use
Dosage
Your doctor will tell you exactly how many capsules to take. For adults, the usual starting dose is 100 mg, 400 mg, or 600 mg once a day.
Method
Take Imatinib Orion capsules with a meal and a large glass of water to help prevent stomach problems. Swallow the capsules whole. If you have trouble swallowing, you can open the capsules and mix the powder with a glass of water or apple juice.
Important
For adults, the daily dose should not exceed 800 mg. Your doctor will determine your maximum dose.
Possible Side Effects
COMMON
- •Headache
- •Feeling tired or weak
- •Nausea, vomiting, diarrhea, indigestion
- •Skin rash
- •Muscle cramps or pain in joints, muscles, or bones
- •Swelling, like around the eyes or ankles
- •Sudden weight gain (due to fluid retention)
- •Symptoms of infection like fever, chills, sore throat, or mouth sores
- •Unexpected bleeding or bruising
- •Loss of appetite, weight loss, or changes in taste
- •Sleep problems (insomnia)
- •Eye discharge, itching, redness, swelling, increased tears, or blurred vision
- •Nosebleeds
- •Stomach pain or bloating, gas, heartburn, or constipation
- •Itching
- •Unusual hair loss or thinning
- •Numbness in hands or feet
- •Mouth sores
- •Joint pain with swelling
- •Dry mouth, dry skin, or dry eyes
- •Decreased or increased skin sensitivity
- •Hot flashes, chills, or night sweats
RARE
- •Chest pain or irregular heartbeat (signs of heart problems)
- •Cough, difficulty breathing, or pain when breathing (signs of lung problems)
- •Dizziness, lightheadedness, or fainting (signs of low blood pressure)
- •Nausea with loss of appetite, dark urine, or yellow skin/eyes (signs of liver problems)
- •Severe skin rash with blisters on lips, eyes, skin, or mouth; peeling skin, fever, raised red or purplish patches, itching, burning, or blister-like rash
- •Severe stomach pain, blood in vomit, stool or urine; or black stools (signs of gastrointestinal problems)
- •Greatly reduced urination or feeling very thirsty (signs of kidney problems)
- •Severe headache, weakness or paralysis in limbs or face, speech problems, or sudden loss of consciousness (signs of nervous system disorders like brain bleeding or swelling)
- •Pale skin, tiredness, shortness of breath, or dark urine (signs of low red blood cells)
- •Eye pain or worsening vision, or bleeding in the eye
- •Bone or joint pain (signs of osteonecrosis)
- •Blisters on skin or mucous membranes (signs of pemphigus)
- •Coldness or numbness in fingers and toes (signs of Raynaud's syndrome)
- •Sudden swelling and redness of the skin (signs of cellulitis)
- •Hearing loss
- •Muscle weakness and cramps with irregular heartbeat (signs of changes in potassium levels in your blood)
- •Bruises
- •Abdominal pain with nausea
- •Muscle cramps with fever, reddish-brown urine, or pain/weakness in muscles (signs of muscle problems)
- •Pelvic pain, sometimes with nausea and vomiting, unexpected vaginal bleeding, dizziness or fainting due to low blood pressure (signs of ovary or uterus problems)
- •Nausea, shortness of breath, irregular heartbeat, cloudy urine, tiredness, and/or joint pain with abnormal lab test results
- •Blood clots in small blood vessels (thrombotic microangiopathy)
- •Confusion
- •Spasms and loss of consciousness (seizures)
- •Nail discoloration
- •Redness and/or swelling of palms and soles, possibly with tingling and burning pain
- •Painful and/or blistering skin lesions
- •Slow growth in children and adolescents
Important Warnings
- Do not take this medicine if you are allergic to imatinib or any other ingredient in the medicine.
- Tell your doctor if you have or have had liver, kidney, or heart problems.
- If you have ever had Hepatitis B, tell your doctor, as Imatinib Orion can reactivate the infection.
- Contact your doctor right away if you notice unusual bruising, bleeding, fever, feeling very tired, or confusion, as these could be signs of serious blood vessel damage.
- Tell your doctor immediately if you gain weight quickly, as this medicine can cause your body to hold too much fluid.
Show 3 more warnings
- This medicine can make you more sensitive to the sun. Protect your skin by covering up and using high-SPF sunscreen.
- Do not use this medicine if you are pregnant or breastfeeding. Women who can get pregnant should use effective birth control during treatment and for 15 days after.
- This medicine may cause dizziness, drowsiness, or blurred vision. Do not drive or operate machinery if you feel these effects.