Ibuxin
Ibuxin is a medicine that contains ibuprofen, which helps to reduce pain, inflammation, and fever.
Form
tabletti, kalvopäällysteinen
Strength
400 mg
Active Ingredient
Ibuprofen
Manufacturer
ratiopharm GmbH
How to Use
Dosage
Take 0.5 to 1 tablet, 1 to 3 times a day as needed.
Method
Swallow the tablet whole with a glass of water.
Important
Do not take more than 3 tablets (1200 mg) in a 24-hour period.
Possible Side Effects
COMMON
- •Heartburn, stomach ache, nausea, vomiting, gas, diarrhea, constipation, or minor stomach bleeding.
RARE
- •Allergic reactions like skin rash, itching, or asthma attacks (which may lower blood pressure).
- •Headache, dizziness.
- •Trouble sleeping, feeling agitated, irritated, or tired.
- •Vision problems.
- •Stomach or intestinal ulcers and possible perforations (holes).
- •Mouth sores or inflammation.
- •Worsening of bowel inflammation (colitis or Crohn's disease).
- •Stomach lining inflammation (gastritis).
- •Skin reactions to sunlight (photosensitivity).
- •Ringing in the ears (tinnitus).
- •Kidney damage.
- •Increased uric acid levels in the blood.
- •Vision loss due to toxicity.
- •Worsening of inflammation linked to infections.
- •Blood cell disorders, with symptoms like fever, sore throat, flu-like symptoms, nosebleeds, or tiredness.
- •Severe allergic reactions like swelling of the face, throat, or tongue, narrowed airways, shortness of breath, fast heart rate, or low blood pressure. These can lead to angioedema or anaphylactic shock.
- •Psychotic reactions, depression.
- •Palpitations (fast or irregular heartbeat), heart failure, heart attack.
- •High blood pressure.
- •Esophagus inflammation, pancreas inflammation, or diaphragm-like narrowing in the intestines.
- •Liver problems (impaired function, damage, failure, acute hepatitis).
- •Severe skin infections with soft tissue problems during chickenpox.
- •Red, non-raised, target-like or circular patches on the body, often with blisters in the middle; skin peeling; sores in the mouth, throat, nose, eyes, and genitals. These serious skin rashes can be preceded by fever and flu-like symptoms.
- •Decreased urine output and fluid retention in the body (causing swelling), which may indicate kidney disease and sometimes kidney failure.
- •Nephrotic syndrome (fluid retention and high protein in urine), inflammatory kidney disease, which may involve acute kidney failure.
- •Chest pain, which could be a sign of a severe allergic reaction called Kounis syndrome.
- •Widespread skin rash, high body temperature, and swollen lymph nodes (DRESS syndrome).
- •Red, widespread, scaly rash with bumps under the skin and blisters, along with fever (Acute Generalized Exanthematous Pustulosis, AGEP). These symptoms usually appear in skin folds, on the body, and on the arms/hands around the start of treatment.
- •Fixed drug eruption (a skin reaction that reappears in the same spot each time you take the medicine).
Important Warnings
- Do not use if you are allergic to ibuprofen or any other ingredients in this medicine.
- Do not use if you have had allergic reactions or asthma worsening from aspirin or other similar pain relievers (NSAIDs).
- Do not use if you have severe heart failure.
- Do not use if you have an active stomach or intestinal ulcer or bleeding.
- Do not use if you have had a stomach or intestinal perforation or bleeding (e.g., black or bloody stools, vomiting blood) linked to previous NSAID use.
Show 9 more warnings
- Do not use if you have a bleeding disorder (like hemophilia) or low platelet count, or if you are taking blood-thinning medicines.
- Do not use if you have an unexplained blood cell formation disorder.
- Do not use if you have severe kidney or liver failure, or a severe heart condition that is not controlled by treatment.
- Do not use if you have bleeding in the brain or any other acute bleeding.
- Do not use during the last 3 months of pregnancy (weeks 28-40).
- Stop using Ibuxin and contact a doctor immediately if you get severe skin reactions like widespread rash with fever, blisters, or skin peeling (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS syndrome, or AGEP).
- Stop using Ibuxin and contact a doctor immediately if you have signs of an allergic reaction like difficulty breathing, swelling of the face/neck, or chest pain.
- If you are taking this medicine for an infection and your symptoms (like pain, swelling, fever) worsen or do not improve, contact a doctor immediately.
- Stop using Ibuxin and contact a doctor immediately if you experience sudden severe stomach pain, bloody diarrhea, or bloody vomiting.
Use in Elderly Patients
Category C
Suitable for older adults, with specific precautions. For short-term use only. Consider adverse renal effect in chronic kidney disease. Do not use in severe renal impairment. Increases swelling, worsens renal and heart failure and causes cardiovascular events. Increases risk of bleeding, especially in the gastrointestinal tract. Consider potential interactions especially with preparations that increase risk of bleeding. (updated 16.9.2024)